Gene News and Research

Latest Gene News and Research

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

Study uncovers new rules for lineage progression

The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing heterogeneity of neurons that regulate endocrine, autonomic and behavioral functions. It not only regulates food consumption, water intake, body temperature, circadian rhythm and sleep to maintain the survival of individual organisms, but also controls puberty onset and reproductive behavior to sustain the breeding population.

17 Nov 2022

Research highlights an understudied aspect of Alzheimer’s disease

Memory loss is often the first sign of Alzheimer's disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first concentrate in the temporal lobes of the brain - the memory area - before spreading to parts of the brain important for thinking and planning.

17 Nov 2022

Omicron BA.2 causes more symptoms and a greater disruption to daily life

In a recent study published in the Nature Communications journal, researchers monitored the changing symptom profiles associated with different severe acute respiratory syndrome CoV-2 (SARS-CoV-2) variants, especially Omicron subvariants BA.1 and BA.2.

16 Nov 2022

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

In a recent study posted to the bioRxiv* preprint server, researchers evaluated responses of natural killer (NK) lymphocytes to VACV (vaccinia virus) infections in vivo.

16 Nov 2022

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports.

16 Nov 2022

Study could form the basis of blood testing for people at high risk of breast cancer

Researchers have found changes in the levels of particular proteins in people's blood up to two years before they were diagnosed with breast cancer.

16 Nov 2022

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).

16 Nov 2022

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

A collaborative study led by the University of Oxford as part of the UK's 100,000 Genomes Project, published in Nature Genetics today, has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukemia (CLL) and associated these with clinical outcomes.

16 Nov 2022

Multilevel Julich Brain Atlas could aid in studying psychiatric and aging disorders

The multilevel Julich Brain Atlas developed by researchers in the Human Brain Project, could help in studying psychiatric and aging disorders by correlating brain networks with their underlying anatomical structure.

16 Nov 2022

Research in young rats shows how hormonal contraceptives may affect the brain

Reproductive health experts consider hormonal contraceptives good choices for adolescents because they're safe and highly effective at preventing pregnancy, but one aspect of their effect on the teenage body remains a mystery – whether and how they modify the developing brain.

16 Nov 2022

Scientists explore links between survival motor neuron protein and sarcopenia

Adopting some of the strategies behind successfully treating the childhood disease spinal muscular atrophy may enable development of therapies to curb the muscle decline that accompanies aging, new research suggests.

15 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

Gene may play a broader role in embryonic organ development

An international study led by the medical Faculty of the University of Bonn has identified a gene that plays an important role in the development of the human embryo. If it is altered, malformations of various organ systems can result.

15 Nov 2022

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

15 Nov 2022

Research sheds light on cardiac pathology mechanisms of COVID-19

Researchers compared cardiac autopsy samples from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive cases with age-matched samples from influenza hemagglutinin 1 neuraminidase 1 (H1N1) cases, non-influenza lymphocytic myocarditis cases, and heart tissue with no inflammation to understand the mechanisms underlying the pathology of the cardiac complications during coronavirus disease 2019 (COVID-19).

15 Nov 2022

Unique cellular signature can accurately detect obstructive sleep apnea in children

Researchers from the University of Missouri School of Medicine have discovered how obstructive sleep apnea (OSA) changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately detect obstructive sleep apnea in children.

15 Nov 2022

Gene News and Research

Latest Gene News and Research

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Study uncovers new rules for lineage progression

Research highlights an understudied aspect of Alzheimer’s disease

Omicron BA.2 causes more symptoms and a greater disruption to daily life

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

Study could form the basis of blood testing for people at high risk of breast cancer

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

Multilevel Julich Brain Atlas could aid in studying psychiatric and aging disorders

Research in young rats shows how hormonal contraceptives may affect the brain

Scientists explore links between survival motor neuron protein and sarcopenia

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

Gene may play a broader role in embryonic organ development

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Research sheds light on cardiac pathology mechanisms of COVID-19

Unique cellular signature can accurately detect obstructive sleep apnea in children

Small molecules found in breast milk may reduce the likelihood of infants developing allergies

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

What are the current challenges and future directions of mRNA nanomedicine?

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