Gene News and Research

Latest Gene News and Research

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

Studying the molecular motion of proteins reveals previously unseen binding sites that could be targeted by new drug candidate molecules.

21 Nov 2022

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

Researchers assessed several approaches for a circulating cell-free deoxyribonucleic acid (cfDNA)-based multi-cancer early detection (MCED) test. Defining the clinical limit of detection (LOD) based on circulating tumor allele fraction (cTAF) enables the comparison of different approaches.

21 Nov 2022

Hungary sees 116% growth in non-invasive prenatal testing

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From BGI Genomics 21 Nov 2022

SARS-CoV-2 infection and mRNA vaccination prime transcriptionally distinct CD4+ T cell memory landscapes

Researchers reported that SARS-CoV-2 infection and mRNA vaccination induce distinct memory T cells.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

Genetic background plays a role in regulating the metabolism of essential polyunsaturated fatty acids

Genetic background has an effect on the metabolism of the essential polyunsaturated fatty acids alpha-linolenic acid and linoleic acid, a recent study from the University of Eastern Finland shows.

21 Nov 2022

Study provides a more accurate tool to stratify patients with HER2-positive breast cancer

Patients with a type of breast cancer called HER2-positive are less likely to survive if their initial treatment fails to eradicate the tumor completely and they have high levels of immune cells called tumor-infiltrating lymphocytes in the residual disease.

21 Nov 2022

The role of bacteria in cancer growth

Tumor-associated microbiota is an important component of the tumor microenvironment (TME) across 33 types of human cancer. However, little evidence is available regarding the spatial distribution and localization of these microbes in tumor cells.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

New gene classifier can predict the risk of cancer cells recurring or progressing

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2022

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Researchers detected a swine influenza A virus (IAV)-infected patient in routine surveillance at the National Influenza Center in Denmark. The detected influenza variant appeared distinct from any variant found previously in Denmark.

18 Nov 2022

Scientists explore bat sarbecovirus isolation in Japan

Researchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Nov 2022

Bombali ebolavirus has been detected among bats in Mozambique

Researchers reported on the detection of Bombali virus (BOMV, of the ebolavirus genus) ribonucleic acid (RNA) among three free-tailed Mops condylurus (Molossidae) bat species in Mozambique.

18 Nov 2022

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

Scientists have developed a clinical WGS workflow that can detect transmission events of a pathogen before they become dominant.

18 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

Researchers examined the prevalence of contraindications to nirmatrelvir-ritonavir (Paxlovid) in hospitalized coronavirus disease 2019 (COVID-19) patients.

17 Nov 2022

Mitochondria plays an important role in signal transduction in innate immune pathways

Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the Faculty of Medicine at Ruhr University Bochum, Germany, recently discovered that mitochondria play an important role in signal transduction in innate immune pathways.

17 Nov 2022

Scientific gathering aims to integrate advances in cancer and aging research

Institute for Research in Biomedicine - IRB Ageing is the main risk factor for the development of cancer, and the features shared by these two biological processes are increasingly evident. This week the Institute for Research in Biomedicine (IRB Barcelona) and the BBVA Foundation are holding the 38th Barcelona Biomed conference "Quantitative dynamics of aging and premalignancy". Held at the Sant Pau Art Nouveau Site on 14, 15 and 16 November, the event will be hosting 21 internationally recognized experts in the field who will present their latest breakthroughs.

17 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Gene News and Research

Latest Gene News and Research

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

Hungary sees 116% growth in non-invasive prenatal testing

SARS-CoV-2 infection and mRNA vaccination prime transcriptionally distinct CD4+ T cell memory landscapes

Study suggests bats are an underrecognized arenavirus reservoir

MIT researchers develop new technique for genome-wide studies of the liver

Genetic background plays a role in regulating the metabolism of essential polyunsaturated fatty acids

Study provides a more accurate tool to stratify patients with HER2-positive breast cancer

The role of bacteria in cancer growth

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

New gene classifier can predict the risk of cancer cells recurring or progressing

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Scientists explore bat sarbecovirus isolation in Japan

Bombali ebolavirus has been detected among bats in Mozambique

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

Mitochondria plays an important role in signal transduction in innate immune pathways

Scientific gathering aims to integrate advances in cancer and aging research

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson