Gene News and Research

Latest Gene News and Research

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to be able to affect the course of this relentless, incurable disease.

26 Dec 2022

Scientists discover nearly 100,000 new types of viruses

The researchers succeeded in identifying new viruses, even specifying which organisms they are likely to attack. Their discovery is expected to help advance the development of repellents for bacteria, fungi and agricultural pests.

26 Dec 2022

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.

23 Dec 2022

Study reveals protective role of CRTC1 in stopping people from overeating high-calorie foods

High-calorie foods - high in fat, oil, and sugar - can taste good but often cause overeating, leading to obesity and major health problems. But what stimulates the brain to cause overeating?

23 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Study shows de novo origination of functional microproteins

In a new study, researchers performed a genomic analysis to investigate the origination of human microproteins of biological importance.

23 Dec 2022

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies.

22 Dec 2022

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene.

22 Dec 2022

Specialized MRI sensor can detect light deep within tissues

Using a specialized MRI sensor, MIT researchers have shown that they can detect light deep within tissues such as the brain.

22 Dec 2022

UC San Diego researchers rewrite the textbook on gene regulation

A fundamental principle of molecular biology governs how proteins are made within the cell, which happens in two stages called transcription and translation.

22 Dec 2022

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.

22 Dec 2022

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome - a rare genetic, neurocognitive disorder.

22 Dec 2022

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.

22 Dec 2022

Study could pave the way for new drug to treat hand osteoarthritis

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

22 Dec 2022

Impact of epigenetics on the clinical management of cancer patients

Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments.

22 Dec 2022

Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

In the largest-ever genetic study of dementia in people of African ancestry, VA researchers identified several genetic risks different from those seen in people of European ancestry.

22 Dec 2022

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

21 Dec 2022

Study reveals why human lymph nodes lose their function with age

A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.

21 Dec 2022

Gene News and Research

Latest Gene News and Research

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

Scientists discover nearly 100,000 new types of viruses

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

Study reveals protective role of CRTC1 in stopping people from overeating high-calorie foods

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Study shows de novo origination of functional microproteins

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

Specialized MRI sensor can detect light deep within tissues

UC San Diego researchers rewrite the textbook on gene regulation

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

Study could pave the way for new drug to treat hand osteoarthritis

Impact of epigenetics on the clinical management of cancer patients

Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

New methods can advance the development of rapid diagnostics for many infectious diseases

Recapitulating early stages of the human body plan in a dish

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Study reveals why human lymph nodes lose their function with age

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