Gene News and Research

Latest Gene News and Research

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Recent evidence has emerged to suggest that age-related macular degeneration (AMD) is a clinical risk factor for increased risk for infection and mortality.

3 Jan 2023

Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic baz1b clues to the evolution of social behaviors in humans and domesticated species.

3 Jan 2023

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Scientists have described the utility of gram-negative bacteria-derived outer membrane vesicles as vaccines and methods to expand their applications.

3 Jan 2023

'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders - especially neurodevelopmental disorders.

3 Jan 2023

What is the impact of COVID-19 on the human genetic architecture?

Researchers recently described the second update on the study of human genetic architecture with respect to the effect of coronavirus disease 2019 (COVID-19).

3 Jan 2023

BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

A new study in the journal Viruses examines the phenomenon of breakthrough infections due to the evasion of T-cell immunity by the Omicron BA.4/BA.5 subvariants, showing this to be due to spike gene mutations.

2 Jan 2023

Mouse study identifies potential targets for treating dry eye disease and corneal injury

People with a condition known as dry eye disease are more likely than those with healthy eyes to suffer injuries to their corneas.

2 Jan 2023

Researchers use engineered proteins to record histories of cellular events

As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using a light microscope.

2 Jan 2023

New method records gene activity patterns and presence of proteins across tissues

A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center.

2 Jan 2023

New insights on the circadian clock of Drosophila melanogaster

The higher the temperatures, the faster physiological processes are. But there is an exception: the so-called circadian clock, which regulates the sleep-wake cycle in organisms.

30 Dec 2022

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine.

28 Dec 2022

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022

Exploring T cell responses during COVID-19 breakthrough infection

Researchers assessed the de novo and recall T cell responses during coronavirus disease 2019 (COVID-19) breakthrough infection.

28 Dec 2022

Scientists explore synthesis of griffithsin in cell-free systems

A new study described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein.

28 Dec 2022

Scientists find key reason for ongoing loss of smell in long-COVID

In a recent study published in the journal Science Translational Medicine, researchers reported that long-term anosmia following coronavirus disease 2019 (COVID-19) could be a result of persistent T-cell mediated inflammation occurring in the olfactory epithelium even after the elimination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the olfactory tissue.

27 Dec 2022

Xanthan gum-based fluid thickener can lower blood glucose levels after eating, study shows

Type 2 diabetes mellitus is a common lifestyle disease that is prevalent worldwide. It can often lead to complications, such as diseases of the heart, and increased risk of death, but preventive measures, such as a healthy diet, can reduce these risks.

27 Dec 2022

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

A Japanese research group has become the first to reveal that the checkerboard-like arrangement of cells in the inner ear's organ of Corti is vital for hearing.

27 Dec 2022

Gene News and Research

Latest Gene News and Research

Researchers identify novel gene mechanism in most aggressive kidney cancers

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

What is the impact of COVID-19 on the human genetic architecture?

BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

Mouse study identifies potential targets for treating dry eye disease and corneal injury

Researchers use engineered proteins to record histories of cellular events

New method records gene activity patterns and presence of proteins across tissues

New insights on the circadian clock of Drosophila melanogaster

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Exploring T cell responses during COVID-19 breakthrough infection

Scientists explore synthesis of griffithsin in cell-free systems

Scientists find key reason for ongoing loss of smell in long-COVID

Xanthan gum-based fluid thickener can lower blood glucose levels after eating, study shows

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

PhD researcher at LifeArc

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