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Epilepsy drug phenytoin causes bone loss in young women

Young women who took the commonly used epilepsy drug phenytoin for one year showed significant bone loss compared to women taking other epilepsy drugs, according to a study published in the April 29, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

28 Apr 2008

More than 40 per cent of smokers tried to quit in 2007

Forty three per cent of England's smokers tried to quit in 2007, and many of them several times - according to Cancer Research UK's director of tobacco studies, Professor Robert West. His findings are presented at the Action on Smoking and Health (ASH) Wales conference in Cardiff today (Monday).

28 Apr 2008

Sensory integration therapy helps children with autism

Parents of children with autism are increasingly turning to sensory integration treatment to help their children deal with the disorder, and they're seeing good results. In 2007, 71 percent of parents who pursued alternatives to traditional treatment used sensory integration methods, and 91 percent found these methods helpful.

27 Apr 2008

Study shows false memories complicate end-of-life treatment decisions

Advance directives, or living wills, may not effectively honor end-of-life wishes because life-sustaining treatment preferences often change without people being aware of the changes, according to a new study co-authored by UC Irvine researchers Peter Ditto and Elizabeth Loftus.

27 Apr 2008

Study looks at anesthetic desflurane and Alzheimer's

In studies of human brain cells, the widely-used anesthetic desflurane does not contribute to increased production of amyloid-beta protein; however, when combined with low oxygen conditions, it can produce more of this Alzheimer's associated protein.

27 Apr 2008

Combining sorafenib with carboplatin/paclitaxel adds no benefit in lung cancer

A clinical trial evaluating the benefit of adding the drug sorafenib to the combination of carboplatin/paclitaxel chemotherapy for lung cancer patients has been stopped based on results from an interim analysis, after an independent data monitoring committee concluded that the study would not meet its primary endpoint of improved overall survival.

26 Apr 2008

Adult participants needed for ADHD study

The Indiana University School of Medicine Department of Psychiatry seeks participants for a study on the effectiveness of an investigational medication for adults with Attention Deficit-Hyperactivity Disorder. The research study also will examine the impact of adult ADHD on families.

26 Apr 2008

Coffee protects some women against breast cancer

Depending on which variant of a certain gene a woman has, a coffee consumption rate of at least two-three cups a day can either reduce the total risk of developing breast cancer or delay the onset of cancer. This is shown in new research from Lund University and Malmo University in Sweden.

24 Apr 2008

Bioartificial kidney speeds recovery, reduces mortality

Another promising clinical trial for the bioartificial kidney is offering researchers even more hope that within the next few years the device will be available to save lives of patients with acute renal failure.

24 Apr 2008

Lower wealth, education and income associated with increased stroke up to age 65

Higher wealth is linked with a lower risk of stroke in Americans between the ages of 50 and 64, but does not predict strokes in those over age 65, researchers reported in Stroke: Journal of the American Heart Association.

24 Apr 2008

Self-referring physicians behind increase in diagnostic imaging

Physicians who refer patients to their own facilities or machines for scans account for much of the increase in diagnostic imaging ordered for privately insured patients said a Baylor College of Medicine expert in a commentary that appears in the current issue of the journal Medical Care.

24 Apr 2008

Early Exit: Estimating and explaining early exit from drug treatment

Almost a quarter of the most problematic drug-users in some areas exit drug treatment programmes before they've even completed 30 days reports a new study published in BioMed Central’s open access Harm Reduction Journal.

24 Apr 2008

Pralatrexate for T-cell lymphoma

The fifth leading cause of cancer in the United States, lymphoma is made up of more than 40 rare and highly diverse diseases that target the body's lymphatic system. Lymphomas include both one of the fastest growing cancers -- Burkitt's lymphoma, which can double in size in as little as a day -- and one of the slowest, chronic lymphocytic leukemia (CLL).

24 Apr 2008

Hepatitis C therapy peginterferon alfa-2b shows promise

The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed previous interferon-based hepatitis C therapies and have advanced liver disease, according to findings from a large, four-year study presented today at the 43rd annual meeting of the European Association for the Study of the Liver (EASL).

24 Apr 2008

Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia

Researchers at the University Hospital of Magdeburg (Germany) have discovered that atrial tachycardia is associated with mitochondrial dysfunction and oxidative stress followed by the activation of the NF-kB signalling pathway with induction of NF-kB target gene expression in atrial tissue.

24 Apr 2008

Metabolic genes tied to inflammatory predictor of heart disease and stroke risk

Two new studies provide evidence that differences in people's blood levels of C reactive protein (CRP) stem in part from natural variation in known metabolic genes. The researchers report their findings in the May American Journal of Human Genetics, a publication of Cell Press.

24 Apr 2008

Racial disparities in smoking cessation treatment

A new study from the American Cancer Society finds black and Hispanic smokers are less likely than whites to receive and use smoking cessation advice and aids.

24 Apr 2008

Smokers more depressed

The risk of suffering depression increases 41% in smokers, in comparison with non-smokers. This was the conclusion of a study undertaken with 8,556 participants by scientists of the University of Navarra, in collaboration with the University of Las Palmas de Gran Canaria and the Harvard School of Public Health (USA), and which demonstrates in a pioneering way the direct relationship between tobacco use and this disease.

24 Apr 2008

Doctors should consider alternatives to antibiotics for sinusitis

When suffering through a sinus infection, many people ask for an antibiotic to speed their recovery. However, a recent review of clinical trials found that while antibiotics can provide minor improvements in uncomplicated sinusitis cases, most patients recover without the drugs within two weeks.

24 Apr 2008

Interventions for enhancing medication adherence

Patients often do not take the medicines their doctors prescribe, and a new review of existing research suggests that there is no proven way to get them to follow directions for long periods.

24 Apr 2008