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Study tests combined targeted radiopharmaceuticals and precision radiation for recurrent prostate cancer

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have opened a clinical trial that will look at whether combining precision radiation with a targeted radioactive therapy drug can help patients with recurrent prostate cancer delay progression, while delaying or avoiding the side effects of long-term hormone therapy.

16 Jan 2026

New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

In a Phase 1 clinical study, researchers led by EPFL and their partners report that a new liver- and gut-targeted oral drug can safely lower triglycerides and other blood lipids.

16 Jan 2026

Smoking cessation drug shows promise for treating cannabis use disorder

A new randomized controlled trial has found promising evidence that the smoking cessation medication varenicline (Chantix/Champix) can help people with cannabis use disorder (CUD) to reduce cannabis use.

15 Jan 2026

Phase II clinical trial shows promising results for novel sepsis drug

Griffith University researchers may have unlocked the secret to treating sepsis, with a Phase II clinical trial in China successfully concluding with promising results.

14 Jan 2026

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.

13 Jan 2026

Trial finds no benefit of anti-inflammatory therapy in trachomatous trichiasis surgery

John Kempen, MD, MPH, PhD, MHS, Director of Epidemiology for Ophthalmology at Mass Eye and Ear and Harvard Medical School, is the lead author of a paper published in The Lancet Global Health, "Evaluation of fluorometholone as adjunctive medical therapy for trachomatous trichiasis surgery (FLAME): a parallel, double-blind, randomised controlled field trial in the Jimma Zone, Ethiopia."

12 Jan 2026

Alliance trial tests proactive chemotherapy dose adjustments for GI cancers

To make cancer care smoother and more effective, the Alliance for Clinical Trials in Oncology has introduced a new clinical trial for people with gastrointestinal cancers, such as cancers of the stomach, colon, and esophagus.

12 Jan 2026

Durvalumab extends survival in small cell lung cancer but raises cost concerns

A new study suggests that the immune checkpoint inhibitor, durvalumab, may offer new treatment options for patients living with small cell lung cancer (SCLC).

9 Jan 2026

George Mason trial: New pill aims to sustain weight loss after GLP-1s

GLP-1 medications like Ozempic and Wegovy have transformed obesity treatment, but maintaining weight loss after the medications stop remains a challenge.

9 Jan 2026

Individualized drug combinations improve cancer treatment outcomes

Researchers at University of California San Diego School of Medicine have led the first clinical trial in the world to show that cancer drug treatments can be safely and effectively personalized based on the unique DNA of a patient's tumor.

8 Jan 2026

Arginine can modify plaque formation on teeth and protect against dental caries

New human clinical trial proves arginine, an amino acid, can modify plaque formation on teeth, thereby protecting against dental caries.

8 Jan 2026

Single-dose oral cholera vaccine shows promising results in early clinical trial

Clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide.

7 Jan 2026

New trial aims to improve both survival and quality of life for men with advanced prostate cancer

The Alliance for Clinical Trials in Oncology has launched a randomized phase III clinical trial called RECIPROCAL (Alliance A032304) to explore whether doctors can optimize the timing of targeted radiation therapy to minimize side effects while preserving efficacy in men with advanced prostate cancer.

5 Jan 2026

Progesterone mimic plus anti-estrogen treatment slows tumor growth in breast cancer patients

A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen treatment for women with breast cancer, a new Cambridge-led trial has found.

5 Jan 2026

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal disease.

30 Dec 2025

High-dose rifampicin does not improve survival in tuberculosis meningitis

Each year, 11 million people worldwide develop tuberculosis, and about 1.4 million die from it. Meningitis occurs in 1–2% of patients and is the most severe complication of tuberculosis, arising when the bacteria reach the brain.

17 Dec 2025

Dinutuximab beta plus chemotherapy shrinks neuroblastoma tumors in children

Children with a rare form of cancer called neuroblastoma which hasn't responded to initial treatment or that has relapsed may benefit from adding antibody treatment to usual chemotherapy, according to new results from a clinical trial.

12 Dec 2025

UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at the University of California, Irvine, has received an $11,999,933 grant from the California Institute for Regenerative Medicine for an unprecedented clinical trial of a novel neural stem cell therapy for Huntington's disease.

12 Dec 2025

Etomidate proves safer than ketamine for emergency intubations

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published Dec. 9 in the New England Journal of Medicine.

12 Dec 2025

Combining inhibitors and chemotherapy enhances treatment for aggressive leukemia subtypes

While patients with acute myeloid leukemia (AML) are routinely treated with chemotherapy and other cell-killing therapies, existing options do not lead to favorable clinical outcomes in all patients.

12 Dec 2025

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Drug Trial News

Study tests combined targeted radiopharmaceuticals and precision radiation for recurrent prostate cancer

New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

Smoking cessation drug shows promise for treating cannabis use disorder

Phase II clinical trial shows promising results for novel sepsis drug

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

Trial finds no benefit of anti-inflammatory therapy in trachomatous trichiasis surgery

Alliance trial tests proactive chemotherapy dose adjustments for GI cancers

Durvalumab extends survival in small cell lung cancer but raises cost concerns

George Mason trial: New pill aims to sustain weight loss after GLP-1s

Individualized drug combinations improve cancer treatment outcomes

Arginine can modify plaque formation on teeth and protect against dental caries

Single-dose oral cholera vaccine shows promising results in early clinical trial

New trial aims to improve both survival and quality of life for men with advanced prostate cancer

Progesterone mimic plus anti-estrogen treatment slows tumor growth in breast cancer patients

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

High-dose rifampicin does not improve survival in tuberculosis meningitis

Dinutuximab beta plus chemotherapy shrinks neuroblastoma tumors in children

UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Etomidate proves safer than ketamine for emergency intubations

Combining inhibitors and chemotherapy enhances treatment for aggressive leukemia subtypes

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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