Gene News and Research

Latest Gene News and Research

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Study uncovers how common genetic mutations cause renal cancer

The understanding of the link between common genetic mutations and certain cancers is increasing.

9 Aug 2022

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

A recent study published in Cell illustrated a human genome map with dosage sensitivity across disorders.

9 Aug 2022

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

Researchers estimated the vaccine effectiveness (VE) of the primary and booster doses of COVID-19 vaccines against reinfection by Omicron BA.5 and BA.2 lineages and severe post-infection outcomes.

9 Aug 2022

Grape consumption alters gene expression in the brain and has positive effects on behavior and cognition

Recent studies released by Dr. John Pezzuto and his team from Western New England University show "astonishing" effects of grape consumption and "remarkable" impacts on health and on lifespans.

9 Aug 2022

Novel AI tools accurately predict the role of DNA’s regulatory elements

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

9 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples.

8 Aug 2022

Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Insights into the products and services of Azenta

This interview talks to Andre Kotze about the different services and products available at Azenta.

From Azenta Life Sciences 8 Aug 2022

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

In a new study, researchers formed the COVID-19 host genetics initiative to compile a genome-wide association meta-analysis of 60 studies from 25 countries.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

In the beginning, there was boredom. Following the emergence of cellular life on earth, some 3.5 billion years ago, simple cells lacking a nucleus and other detailed internal structure dominated the planet. Matters would remain largely unchanged in terms of evolutionary development in these so-called prokaryotic cells - the bacteria and archaea - for another billion and a half years.

8 Aug 2022

Optically controlled local heat-pulse method manipulates temperature in cells

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and leads to malignant hyperthermia

8 Aug 2022

Gene News and Research

Latest Gene News and Research

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Study uncovers how common genetic mutations cause renal cancer

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

Grape consumption alters gene expression in the brain and has positive effects on behavior and cognition

Novel AI tools accurately predict the role of DNA’s regulatory elements

Overnight EEG studies may help inform care for girls with Rett syndrome

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Disruption of the circadian clocks plays a key role in weight gain

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Research progress on the three-dimensional interaction between virus and host genome

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Insights into the products and services of Azenta

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

Terminally exhausted T cells may remain competent for transcription, researchers say

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

Optically controlled local heat-pulse method manipulates temperature in cells

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