Gene News and Research

Latest Gene News and Research

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

New imaging approach could help accelerate the development of new treatments for eye diseases

Researchers have developed a simple and fast way to perform optoretinography, an imaging technique that measures light-induced functional activity in the eye's retina, the network of neurons in the back of our eyes responsible for detecting light and initiating vision.

22 Sep 2022

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

With a five-year, $126 million grant from the National Institutes of Health, a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas.

22 Sep 2022

New board members bring significant leadership experience in the biotech sector

Aspect Biosystems, a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how we treat disease, is pleased to announce the appointment of three new members to its Board of Directors: Dr. Nancy Krieger, Dr. Don Haut, and Dr. Devyn Smith.

From Aspect Biosystems 22 Sep 2022

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Organoids - lab grown cells or tissues that resemble organs - serve as a new tool for disease modeling, but researchers often have difficulty replicating the biophysical conditions in which the organs operate within the body.

22 Sep 2022

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

The prevalence, age of onset, and clinical symptoms for virtually all neuropsychiatric disorders differ between men and women. Among the disorders with pronounced sex bias are Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), where the ratio of males/females diagnosed is approximately 4 to 1.

21 Sep 2022

Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

New genetic discovery improves understanding of congenital heart disease

A new study led by the Masonic Medical Research Institute published in the journal Cells shows for the first time that a particular gene, called VGLL4, is required for embryo development but is dispensable for myocardial growth.

21 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients.

21 Sep 2022

Evidence A.2 lineage of monkeypox is mutating

In a recent study posted to the bioRxiv* preprint server, a team of researchers from India analyzed the whole genome sequences of the monkeypox virus isolated from monkeypox patients with and without international travel histories to understand the phylogenetic relations and genomic evolution of the virus that could contribute to higher transmission rates.

21 Sep 2022

NPDPSC at Case Western Reserve University to receive CDC funding for better understanding of prion diseases

The National Prion Disease Pathology Surveillance Center at Case Western Reserve University will receive up to $20 million in funding as part of a grant renewal from the Centers for Disease Control and Prevention (CDC) to better understand how and why prion diseases––degenerative brain conditions found in both humans and animals - develop and spread.

20 Sep 2022

Humanized zebrafish could aid in the search for MS drugs

The zebrafish should be known to many aquarium enthusiasts mainly because of its striking pigmentation. However, the characteristic black-blue stripes, to which the animal owes its name, only form over time.

20 Sep 2022

Epigenetic treatment can promote neuronal regrowth in the spinal cord after injury

Currently, spinal cord injury does not have any effective treatments; physical rehabilitation can help patients regain some mobility, but for severe cases the outcomes are extremely limited by the failure of spinal neurons to regenerate naturally after injury.

20 Sep 2022

Epigenetic gene silencing found to be a predictive factor for aggressive breast and ovarian cancer

In a recent study published in JAMA Oncology, investigators from the University of Bergen, in collaboration with the Women's Health Initiative study in the US, reported epigenetic gene silencing in normal tissue to be a predictive factor for triple-negative breast cancer (TNBC) as well as high-grade serous ovarian cancer (HGSOC).

20 Sep 2022

Study identifies genetic variation linked with posterior urethral valves in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a study published today in eLife suggests.

20 Sep 2022

Scientists find evidence of fungal organism Histoplasma capsulatum in Antarctica

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20 Sep 2022

Gene News and Research

Latest Gene News and Research

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

New imaging approach could help accelerate the development of new treatments for eye diseases

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

New board members bring significant leadership experience in the biotech sector

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

Virology of the human monkeypox virus

New genetically-targeted MND therapy could be a turning point for patient care

New genetic discovery improves understanding of congenital heart disease

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Common genetic variants of APOE associated with COVID mortality

Why fatigue from long COVID goes beyond simply feeling tired

Evidence A.2 lineage of monkeypox is mutating

NPDPSC at Case Western Reserve University to receive CDC funding for better understanding of prion diseases

Humanized zebrafish could aid in the search for MS drugs

Epigenetic treatment can promote neuronal regrowth in the spinal cord after injury

Epigenetic gene silencing found to be a predictive factor for aggressive breast and ovarian cancer

Study identifies genetic variation linked with posterior urethral valves in males

Scientists find evidence of fungal organism Histoplasma capsulatum in Antarctica

eBook: Using iPSCs models for human disease research and drug discovery eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson