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Can your diet affect fertility? Gut-linked dietary score reveals surprising risk pattern

A cross-sectional study of over 3,000 U.S. women found a non-linear link between a gut microbiota-based dietary index (DI-GM) and infertility. Risk decreased with healthier diets but unexpectedly rose beyond a certain threshold score.

4 May 2025

Semaglutide clears liver inflammation and cuts fibrosis in MASH patients, trial shows

A phase 3 trial shows that once-weekly semaglutide significantly improves liver histology in patients with metabolic dysfunction-associated steatohepatitis (MASH). The interim results also reveal meaningful weight loss and improved cardiometabolic markers, with a favorable safety profile.

4 May 2025

Black coffee improves insulin sensitivity in women, study finds

Two daily cups of coffee, especially black, are linked to lower insulin resistance and fasting insulin levels in Korean women, suggesting coffee may improve glucose metabolism. The effect was not observed with coffee containing sugar or cream.

4 May 2025

Phthalates in plastics linked to over 350,000 heart deaths worldwide

A global modeling study in eBioMedicine links phthalate exposure from plastics, especially DEHP metabolites, to over 356,000 cardiovascular deaths in 2018. Exposure was highest in Asia, the Middle East, and Africa, disproportionately affecting lower-income countries.

4 May 2025

Ultra-processed foods linked to higher psoriasis risk

A large UK Biobank study found that higher consumption of ultra-processed foods (UPFs) is associated with an increased risk of developing psoriasis. Each 10% increase in UPF intake raised psoriasis risk by 6%, with obesity and inflammation partially mediating this effect.

4 May 2025

Melanoma cases climb amid declining sunscreen use in Canada

Despite decades of public health messaging, Canadians are spending more time in the sun and using less sun protection – raising alarms among researchers as melanoma cases continue to climb.

3 May 2025

Ten year study confirms effectiveness of two-week radiotherapy for prostate cancer

Prostate cancer is the most commonly diagnosed cancer in men worldwide, accounting for more than 1.4 million new cases each year.

3 May 2025

Gene-edited immune cells show promise against advanced GI cancers

Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers.

3 May 2025

Medicaid unwinding may have put opioid recovery care at risk

The massive national effort to return the Medicaid enrollment process to its pre-pandemic rules starting in April 2023 may have disrupted the care of people receiving treatment for opioid addiction, a new University of Michigan study suggests.

3 May 2025

New research maps neural overlap in insomnia, depression, and anxiety

New research from the Netherlands Institute for Neuroscience maps the similarities and differences between the three most common brain disorders.

3 May 2025

RNA editing enzyme found to trigger neuroinflammation in Parkinson's

Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage.

3 May 2025

Medicaid enrollment drops linked to disrupted care for young people

Children and young adults with depression, schizophrenia, ADHD, asthma and epilepsy can get great relief from medications to control their symptoms, helping them stay in school or work and prepare for their futures.

3 May 2025

New three-part antivenom cocktail protects against the world’s deadliest snakes

Scientists developed a groundbreaking antivenom cocktail using antibodies from a hyperimmune human donor and a small-molecule inhibitor that protected mice from deadly bites of 19 diverse snakes. This approach could lead to a universal antivenom for the world’s most dangerous snakes, overcoming the limitations of current species-specific treatments.

2 May 2025

Are one-year-olds in Australia eating right? New study reveals nutrient gaps

A study from the ORIGINS cohort in Western Australia assessed the diets of one-year-old children, comparing intake to national guidelines. While most nutrient targets were met, key shortfalls in iodine and excessive sodium intake raised concerns, especially for breastfed infants.

2 May 2025

Study shows brain estrogen directly regulates appetite in mice

Researchers in Japan found that estrogen produced within the brain, called neuroestrogen, suppresses appetite and reduces body weight in mice by enhancing MC4R expression. The study also showed that neuroestrogen boosts leptin sensitivity, suggesting new targets for obesity treatment.

2 May 2025

Stenting improves long term outcomes in CTO PCI patients

In patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI), stenting demonstrated improved long-term survival and fewer cardiac arrests at one year.

2 May 2025

Heat triggers sperm activation for fertilization in mammals

In mammals - including us humans - sperm are surprisingly picky about temperature, thriving best in conditions a few degrees cooler than normal body temperature.

2 May 2025

Early TAVR shows greatest stroke reduction in patients aged 65 to 70

New analysis from the EARLY TAVR trial showed patients between the age of 65 and 70 years old derived the most benefits of a strategy of early intervention with transcatheter aortic valve replacement (TAVR) compared to other age groups, especially in regards to stroke risk, and in regards to the composite of death, stroke, and heart failure hospitalization.

2 May 2025

HO-1 regulates liver fibrosis in NAFLD through the SIRT1 TGF-β Smad3 pathway

Heme oxygenase 1 (HO-1) has an influential yet insufficiently investigated effect on Sirtuin 1 (SIRT1), a histone deacetylase activated by nicotinamide adenine dinucleotide, which may impact the transforming growth factor-β (TGF-ß)/Smad3 pathway in nonalcoholic fatty liver disease (NAFLD)-related liver fibrosis.

2 May 2025

New albumin-based vaccine shows promise for mucosal immunity

Vaccines save millions of lives every year, but there is still an urgent need for more efficient vaccines. Strategies to combat serious outbreaks of viral infections are particularly important.

2 May 2025