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PolyMedix receives FDA regulatory clearance for PMX-30063 IND application

PolyMedix, Inc. an emerging biotechnology company focused on developing new therapeutic drugs to treat infectious diseases and acute cardiovascular disorders, has received regulatory clearance from the United States Food and Drug Administration (FDA) for its Investigational New Drug (IND) application for PMX-30063, a synthetic defensin-mimetic antibiotic.

11 Nov 2010

Guardian examines former Pres. Bush's reflection on PEPFAR in new memoir

The Guardian examines the reflections of former President George W. Bush on the $15bn President's Emergency Plan for Aids Relief (PEPFAR) which distributed antiretroviral drugs to keep people with HIV alive, as the president describes in his recently released memoir, Decision Points.

11 Nov 2010

PolyMedix announces publication of defensin-mimetic compounds in Molecular Oral Microbiology

PolyMedix, Inc. an emerging biotechnology company focused on developing new therapeutic drugs to treat infectious diseases and acute cardiovascular disorders, announced that data from two separate pre-clinical research studies were published in the December issue of Molecular Oral Microbiology.

10 Nov 2010

Researchers find text messages to HIV patients improve adherence, health outcomes in Kenya trial

Using mobile-phone text messages to remind HIV patients to take their dose of life-saving medications can give a major boost to drug adherence, according to an innovative trial in Kenya unveiled on Tuesday, Agence France-Presse reports.

10 Nov 2010

Vertex to enroll additional treatment arm in telaprevir/VX-222 Phase 2 clinical trial for HCV

Vertex Pharmaceuticals Incorporated today announced plans to enroll an additional treatment arm as part of its ongoing Phase 2 clinical trial evaluating 12-week regimens of Vertex's lead investigational hepatitis C virus (HCV) protease inhibitor, telaprevir, in combination with its lead investigational HCV polymerase inhibitor, VX-222.

10 Nov 2010

Egrifta receives FDA approval for treatment of HIV-lipodystrophy

The U.S. Food and Drug Administration today approved Egrifta (tesamorelin) to treat HIV patients with lipodystrophy, a condition in which excess fat develops in different areas of the body, most notably around the liver, stomach, and other abdominal organs. The condition is associated with many antiretroviral drugs used to treat HIV.

10 Nov 2010

Opinions: G20 development approach; defense of DDT for malaria control; U.S. foreign aid; human trafficking

Leaders have been debating how to 'rebalance' the global economy and reform financial institutions - all challenging subjects. But I also am reminding my colleagues that all these goals, however crucial, are insufficient, Lee Myung-bak, the president of the Republic of Korea, writes in a Washington Post opinion piece.

10 Nov 2010

Cholera outbreak in PNG makes officials wary

Cholera has been confirmed as the cause of death of 16 persons on a remote island in Papua New Guinea which is close to Australia's maritime border. The first case was detected on Daru Island in Western Province three weeks ago. Since then 12 adults and 4 children have died, and 320 others have been treated for the infection.

10 Nov 2010

Fibroblast growth factor-2 stimulates periodontal regeneration: Study

It is well known that oral infection progressively destroys periodontal tissues and is the leading cause of tooth loss in adults. A major goal of periodontal treatment is regeneration of the tissues lost to periodontitis. Unfortunately, most current therapies cannot predictably promote repair of tooth-supporting defects. A variety of regenerative approaches have been used clinically using bone grafts and guiding tissue membranes with limited success.

10 Nov 2010

Preclinical data from Idera's autoimmune and inflammatory disease program presented at 74th ACR

Idera Pharmaceuticals, Inc. today announced two presentations of preclinical data from its autoimmune and inflammatory disease program at the 74th Annual Scientific Meeting of the American College of Rheumatology (ACR) in Atlanta, Georgia. One presentation is entitled "IMO-3100, a Toll-like Receptor (TLR) Antagonist, Suppresses TLR7- and TLR9-mediated Immune Responses in Non-human Primates" (#856).

10 Nov 2010

Regional workshop to discuss diarrheal disease solutions for Asia

Each year, diarrheal disease claims the lives of 1.3 million children under five worldwide and hospitalizes millions more. The vast majority of these deaths occur in developing countries of Asia and Africa, but fortunately, interventions exist that can greatly reduce deaths and save lives. To bring attention to the solutions available today for defeating diarrhea, the Vietnam Ministry of Health, the National Pediatric Hospital of Vietnam, and PATH are hosting a two-day regional workshop where they will present the evidence and lessons learned from initiatives currently underway.

10 Nov 2010

NHLBI launches new campaign to highlight common COPD symptoms

The number of Americans who report being aware of chronic obstructive pulmonary disease, or COPD, increased by 4 percentage points between 2008 and 2010, but many people at risk are still unaware of the disease, according to mailed survey results released today by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.

10 Nov 2010

Pres. Obama emphasizes U.S.-Indian partnerships to track, fight diseases

On his final day in India as part of his 10-day Asia-Pacific tour, President Barack Obama on Monday addressed the joint session of the Indian Parliament in New Dehli, where he emphasized the importance of U.S.-Indian partnerships to tackle disease and improve education, Indo-Asian News Service/Hindustan Times reports (11/8).

10 Nov 2010

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

A vaginal gel that affords both contraception and HIV protection using nanoparticles that carry bee venom is one of the bold, unconventional ideas that won a 2010 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation.

10 Nov 2010

Popular antimicrobial chemicals may not be safe for human health and environment

Killing microorganisms has become a national obsession. A pair of antimicrobial compounds known as triclosan and triclocarban are lately the weapons of choice in our war of attrition against the microbial world. Both chemicals are found in an array of personal care products like antimicrobial soaps, and triclosan also is formulated into everyday items ranging from plastics and toys to articles of clothing.

10 Nov 2010

Malaria drug artesunate found more effective than quinine at preventing severe falciparum malaria deaths in children, study says

Researchers found that the death rate among children diagnosed with severe falciparum malaria was almost one-fourth lower when they received the drug artesunate rather than the standard treatment of quinine, according to research which was presented at the American Society for Tropical Medicine and Hygiene (ASTMH) over the weekend and published Monday in the Lancet, HealthDay News/U.S. News and World Report writes.

10 Nov 2010

Miriam Hospital receives NIH grants to improve HIV treatment for jail inmates

The Miriam Hospital received three of the 12 newly awarded grants from the National Institutes of Health (NIH) aimed at improving HIV prevention and treatment of prison and jail inmates.

10 Nov 2010

Cholera confirmed in Haiti's capital as health ministry says outbreak has killed 544 so far

Haiti's cholera outbreak appears to have spread to its capital, "imperiling nearly 3 million people living in Port-au-Prince, nearly half of them in unsanitary tent camps for the homeless from the Jan. 12 earthquake," the Associated Press/KIRO reports.

10 Nov 2010

Flu vaccination programs can protect employee health, save businesses money

Each year, influenza poses a tremendous burden on working adults and the many businesses that employ them, contributing to absenteeism and lost productivity. Yet, annual influenza immunization rates remain very low. New data out today show that employer-sponsored influenza vaccination programs held early in the flu season not only protect employee health, but save businesses money.

10 Nov 2010

L. reuteri Prodentis effective for treating chronic periodontitis

The study shows that L. reuteri Prodentis acts synergistically with standard treatment (scaling and root plaining, SRP) to significantly reduce probing pocket depth (PPD) and clinical attachment level (CAL) which are the two most important parameters to assess the severity of periodontitis. Furthermore L. reuteri Prodentis reveals - as the first probiotic ever - significant reductions of three different pathogens in patients with chronic periodontitis.

10 Nov 2010

Disease/Infection News

PolyMedix receives FDA regulatory clearance for PMX-30063 IND application

Guardian examines former Pres. Bush's reflection on PEPFAR in new memoir

PolyMedix announces publication of defensin-mimetic compounds in Molecular Oral Microbiology

Researchers find text messages to HIV patients improve adherence, health outcomes in Kenya trial

Vertex to enroll additional treatment arm in telaprevir/VX-222 Phase 2 clinical trial for HCV

Egrifta receives FDA approval for treatment of HIV-lipodystrophy

Opinions: G20 development approach; defense of DDT for malaria control; U.S. foreign aid; human trafficking

Cholera outbreak in PNG makes officials wary

Fibroblast growth factor-2 stimulates periodontal regeneration: Study

Preclinical data from Idera's autoimmune and inflammatory disease program presented at 74th ACR

Regional workshop to discuss diarrheal disease solutions for Asia

NHLBI launches new campaign to highlight common COPD symptoms

Pres. Obama emphasizes U.S.-Indian partnerships to track, fight diseases

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

Popular antimicrobial chemicals may not be safe for human health and environment

Malaria drug artesunate found more effective than quinine at preventing severe falciparum malaria deaths in children, study says

Miriam Hospital receives NIH grants to improve HIV treatment for jail inmates

Cholera confirmed in Haiti's capital as health ministry says outbreak has killed 544 so far

Flu vaccination programs can protect employee health, save businesses money

L. reuteri Prodentis effective for treating chronic periodontitis

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