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New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia (B-cell ALL), even when the drug doesn't meet the FDA's strict manufacturing standards.

19 Oct 2021

Genetic testing in siblings of newborns with cancer susceptibility genes could reduce deaths by 50%

Genetic testing of the siblings of newborns found to have mutations in any one of 11 genes most commonly associated with childhood-onset cancers could reduce deaths from these rare cancers by about 50%, suggests a study funded by the National Institutes of Health.

19 Oct 2021

Researchers unravel basic mechanisms of learning new words in sleeping toddlers

Very young children learn words at a tremendous rate. Now researchers at the Center for Mind and Brain at the University of California, Davis, have for the first time seen how specific brain regions activate as two-year-olds remember newly learned words - while the children were sleeping.

19 Oct 2021

Study reveals the importance of COVID-19 testing in reopening of schools

A new qualitative study examines the attitudes of school administrators, teachers, parents, and students towards the implementation of COVID-19 testing.

19 Oct 2021

Children with disabilities face special back-to-school challenges

Christopher Manzo, a boy with curly brown hair and bright-blue-and-yellow glasses, has lived a third of his five years at home because of the pandemic.

19 Oct 2021

Rewarming after cooling therapy increases the odds of seizures in oxygen-deprived newborns

Oxygen-deprived newborns who undergo cooling therapy to protect their brains are at an elevated risk of seizures and brain damage during the rewarming period, which could be a precursor of disability or death, a new study by a team of researchers led by a UT Southwestern pediatrician suggests.

19 Oct 2021

Professor Liston’s latest book helps young children to learn about vaccines

The Professor Adrian Liston, Senior Group Leader at the Babraham Institute, and artist Dr Sonia Agüera-Gonzalez have published a captivating story book to teach children about the immune system and why vaccinations are important.

19 Oct 2021

SARS-CoV-2 antibodies detected in breast milk of vaccinated mothers

Now, a new medRxiv* preprint study finds mothers vaccinated either one of the messenger RNA (mRNA) vaccines transferred neutralizing antibodies and cytokines, including interferon-gamma (IFNγ), to a breastfeeding child. Additionally, the humoral response in breastmilk was effective in neutralizing four variants of concern.

18 Oct 2021

Telehealth to the rescue for children’s mental health during COVID

A new study concludes that the lack of transportation led to impairments in child mental health services.

18 Oct 2021

Breastfeeding and later introduction to gluten may have a protective effect against type 1 diabetes

Research on the role of diet in the development of type 1 diabetes is generally of low evidence, but there are some high-quality studies indicating that longer breastfeeding and later introduction to gluten may reduce the risk of disease.

18 Oct 2021

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder.

18 Oct 2021

New study focuses on getting shy children to face their fears

Getting shy children to 'face their fears' and coaching parents in exposure therapy is the focus of a new study at The University of Queensland.

18 Oct 2021

Accelerated regime of preventative drugs could prevent malaria infection and deaths in Africa

Malaria infection and deaths could be avoided by more than half a million young children thanks to an accelerated regime of preventative drugs being rolled in four African countries, says global health agency Unitaid.

18 Oct 2021

Mix-and-match booster shots beneficial in boosting SARS-CoV-2 immunity

Should you get a second dose of the same vaccine if you’ve received the one-dose Johnson & Johnson shot? According to new clinical trial results published on the preprint medRxiv* server, a booster shot of a messenger RNA (mRNA) vaccine may increase your chances of neutralizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Oct 2021

Devastating genetic disease in children may be treatable in adulthood

A devastating genetic disease called CDKL5 deficiency disorder (CDD), which strikes in early childhood, may be significantly treatable even in adulthood, a new study from the Perelman School of Medicine at the University of Pennsylvania suggests.

15 Oct 2021

Common treatment for MIS-C patients likely works by depleting neutrophils

Intravenous immune globulin (IVIG) — a common treatment for multisystem inflammatory syndrome in children (MIS-C) — likely works by depleting immune cells called neutrophils, according to a recent study funded by the National Institutes of Health.

15 Oct 2021

Pandemic-related grief associated with lower levels of mother-infant bonding

The emotional connection between a mother and her newborn baby can lay the foundation for the child's development and the family's outcomes.

15 Oct 2021

Children with cerebral palsy benefit most from higher doses of CIMT therapy

Children with cerebral palsy can gain greater use of an impaired arm and hand with larger doses of Constraint-Induced Movement Therapy (CIMT) – without increasing stress for parents, according to a new study by researchers at Virginia Tech's Fralin Biomedical Research Institute at VTC, UVA Children's, The Ohio State University, and Nationwide Children's Hospital.

15 Oct 2021

Connection to nature during the pandemic linked with children's wellbeing

Children from less affluent backgrounds are likely to have found COVID-19 lockdowns more challenging to their mental health because they experienced a lower connection with nature than their wealthier peers, a new study suggests.

15 Oct 2021

Research receives $1.74 million to explore how prenatal alcohol exposure leads to 'anxious' offspring

A researcher at Binghamton University, State University of New York has received a $1.74 million, five-year grant from the National Institutes of Health to explore how prenatal alcohol exposure leads to 'anxious' offspring.

15 Oct 2021

Child Health News

New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

Genetic testing in siblings of newborns with cancer susceptibility genes could reduce deaths by 50%

Researchers unravel basic mechanisms of learning new words in sleeping toddlers

Study reveals the importance of COVID-19 testing in reopening of schools

Children with disabilities face special back-to-school challenges

Rewarming after cooling therapy increases the odds of seizures in oxygen-deprived newborns

Professor Liston’s latest book helps young children to learn about vaccines

SARS-CoV-2 antibodies detected in breast milk of vaccinated mothers

Telehealth to the rescue for children’s mental health during COVID

Breastfeeding and later introduction to gluten may have a protective effect against type 1 diabetes

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

New study focuses on getting shy children to face their fears

Accelerated regime of preventative drugs could prevent malaria infection and deaths in Africa

Mix-and-match booster shots beneficial in boosting SARS-CoV-2 immunity

Devastating genetic disease in children may be treatable in adulthood

Common treatment for MIS-C patients likely works by depleting neutrophils

Pandemic-related grief associated with lower levels of mother-infant bonding

Children with cerebral palsy benefit most from higher doses of CIMT therapy

Connection to nature during the pandemic linked with children's wellbeing

Research receives $1.74 million to explore how prenatal alcohol exposure leads to 'anxious' offspring

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