T Cell News and Research

Latest T Cell News and Research

Lung biomarkers may predict severe COVID-19

Two University of New Mexico researchers postulate certain specific biomarkers' relevance in predicting the potential for progression to severe COVID-19 in a paper published on the preprint server bioRxiv*

27 Oct 2020

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Administering radiation therapy to multiple myeloma patients waiting for CAR T cells to be manufactured was found to be safe and undisruptive to CAR T therapy, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania to be presented Tuesday, October 27, at the virtual American Society for Radiation Oncology Annual Meeting (Abstract #35562).

27 Oct 2020

Cellular senescence variations may control health and onset of age-related diseases

Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases.

27 Oct 2020

Anti-inflammatory mediator may play key role in wound healing

"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr. Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.

27 Oct 2020

Expression of a specific gene could regulate feelings of fear and its extinction

Fear and fear extinction learning are adaptive processes caused by molecular changes in specific brain circuits, and they're perturbed in conditions such as anxiety and post-traumatic stress disorder.

27 Oct 2020

Tiny gold nanotubes could help treat mesothelioma

Gold nanotubes - tiny hollow cylinders one thousandth the width of a human hair - could be used to treat mesothelioma, a type of cancer caused by exposure to asbestos, according to a team of researchers at the Universities of Cambridge and Leeds.

27 Oct 2020

Researchers identify a new way to prevent skin reactions in cancer patients

Using the body's immune system to fight cancer has great potential, but can also bring serious side effects, including itchy and painful skin reactions.

27 Oct 2020

Researchers identify effective way to protect vulnerable people from COVID-19

T-cells taken from the blood of people who recovered from a COVID-19 infection can be successfully multiplied in the lab and maintain the ability to effectively target proteins that are key to the virus's function, according to a new study published Oct. 26 in Blood.

27 Oct 2020

Multimodal mapping of immune landscape in pancreatic cancer could guide personalized therapies

Pancreatic cancer has remained resistant to immunotherapies that are revolutionizing the treatment of many types of cancer.

27 Oct 2020

About 15% of COVID-19-related deaths linked to long-term exposure to air pollution

Long-term exposure to air pollution has been linked to an increased risk of dying from COVID-19 and, for the first time, a study has estimated the proportion of deaths from the coronavirus that could be attributed to the exacerbating effects of air pollution for every country in the world.

27 Oct 2020

Novel insights open up new avenues for treating autoimmune conditions

Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting as "brakes" on the immune response so it doesn't go overboard.

27 Oct 2020

Genome-wide screens reveal new helpful and harmful COVID-19 related genes

Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus.

27 Oct 2020

Scientists identify new target for developing novel drugs against several types of cancer

The Bcl-2 protein family comprises anti- and proapoptotic members, i.e. they protect the cell from death or favour it.

27 Oct 2020

Study better reveals the function and behavior of macrophages in cancer growth

Macrophages, cells that help engulf and destroy harmful organisms in the body, tend to be characterized as the Jekyll and Hyde of the immune system.

27 Oct 2020

Phase 1 trial results of gorilla adenovirus vaccine for COVID-19

A recent study published on the preprint server bioRxiv* in October 2020 reports the development of a novel vaccine based on a simian adenoviral vector obtained from a group C gorilla isolate called GRAd32. This could help speed up vaccine development.

26 Oct 2020

Researchers generate a transcriptomic map of the COVID brain

COVID-19 is known to be associated with multiple changes in gene expression, but many of these are also seen in chronic brain conditions as well as in some abnormal mental conditions. A recent study published on the preprint server bioRxiv in October 2020 uncovers the molecular basis of this association.

26 Oct 2020

New peptide derivatives that target the SARS-CoV-2 spike protein

In a new study published in the journal Cellular and Molecular Bioengineering, researchers report peptide derivatives, or peptidomimetics, based on the circle residues involved in the interaction of the spike protein and ACE2.

26 Oct 2020

Transcriptomics identifies possible COVID-19 therapies

By using a diverse set of transcriptomic SARS-CoV-2 signatures, US researchers put to use their previously developed drug repositioning pipeline to pinpoint potential drug candidates for the treatment of coronavirus disease (COVID-19). The study is currently available on bioRxiv preprint server.

26 Oct 2020

Nasal spray formulation of ivermectin for COVID-19 shows promise in pigs

Researchers in Argentina have conducted a pre-clinical study demonstrating the safety and pharmacokinetic performance of a new nasal spray formulation designed to suppress the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

26 Oct 2020

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

A new study published on the preprint server bioRxiv* in October 2020 reports the discovery of important viral genomic features that are crucial to its replication in the human airway cells, and its enhancing mutations which increase the rate of replication and determine its target cells.

26 Oct 2020

T Cell News and Research

Latest T Cell News and Research

Lung biomarkers may predict severe COVID-19

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Cellular senescence variations may control health and onset of age-related diseases

Anti-inflammatory mediator may play key role in wound healing

Expression of a specific gene could regulate feelings of fear and its extinction

Tiny gold nanotubes could help treat mesothelioma

Researchers identify a new way to prevent skin reactions in cancer patients

Researchers identify effective way to protect vulnerable people from COVID-19

Multimodal mapping of immune landscape in pancreatic cancer could guide personalized therapies

About 15% of COVID-19-related deaths linked to long-term exposure to air pollution

Novel insights open up new avenues for treating autoimmune conditions

Genome-wide screens reveal new helpful and harmful COVID-19 related genes

Scientists identify new target for developing novel drugs against several types of cancer

Study better reveals the function and behavior of macrophages in cancer growth

Phase 1 trial results of gorilla adenovirus vaccine for COVID-19

Researchers generate a transcriptomic map of the COVID brain

New peptide derivatives that target the SARS-CoV-2 spike protein

Transcriptomics identifies possible COVID-19 therapies

Nasal spray formulation of ivermectin for COVID-19 shows promise in pigs

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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