T Cell News and Research

Latest T Cell News and Research

Research shows a unique T cell receptor repertoire in MIS-C patients

Children with coronavirus disease 2019 (COVID-19) sometimes develop the Multisystem Inflammatory Syndrome in Children (MIS-C), which is associated with high morbidity. The underlying T-cell associated mechanism is described by researchers in a new study published on the preprint server bioRxiv in November 2020, as a response to superantigen activation.

11 Nov 2020

Men and women may require different brain tumor therapy, study finds

The current study shows that the sex differences in the tumor phenotype vary with the effect of the enhancer regulatory molecule bound to Brd4 on the course of stem cell-like differentiation in male and female GBM cells. Inhibition of Brd4 by genetic and pharmacological factors also varies in males and females, both in vivo and in vitro.

11 Nov 2020

Biologists investigate how molecular chaperones dissolve protein aggregates linked to Parkinson's

In many neurodegenerative diseases like Parkinson's, protein aggregates form in the brain and are assumed to contribute to neuronal cell death.

11 Nov 2020

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Promising clinical results with combination treatments for patients with melanoma and lung cancer highlight immunotherapy advances being presented by researchers from The University of Texas MD Anderson Cancer Center at The Society for Immunotherapy of Cancer 35th Anniversary Annual Meeting & Pre-Conference Programs.

11 Nov 2020

Discovery of novel hidden gene in SARS-CoV-2

A team of researchers from Germany, Taiwan, and the United States has identified and characterized a new hidden gene in SARS-CoV-2 that is also present in Guangxi pangolin coronaviruses – though, curiously, absent in closely related pangolin and bat coronaviruses.

11 Nov 2020

Researchers uncover potential genetic target for treating endometriosis

Michigan State University researchers have identified a potential genetic target for treating an especially painful and invasive form of endometriosis.

11 Nov 2020

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Tohoku University scientists have found that human editing enzymes are likely behind a type of mutation in the COVID-19 virus that stimulates the release of pro-inflammatory molecules called cytokines by immune cells in the body.

11 Nov 2020

Rheumatoid arthritis may increase risk of dying from COVID-19

Researchers in New Zealand and Australia have conducted a study showing that people with rheumatoid arthritis may be at an increased risk of death if they develop coronavirus disease 2019 (COVID-19) after becoming infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 Nov 2020

Team sport improves blood pressure, vascular function in postmenopausal women

Team sport effectively counteracts diminished vascular function in women with high blood pressure, even several years after the onset of menopause.

11 Nov 2020

Researchers identify new prognostic markers for colon cancer

The gut-associated lymphoid tissue represents an integral part of the immune system. Among the powerful players of the mucosa-associated lymphoid tissue are isolated lymphoid structures (ILSs).

11 Nov 2020

Microbes in the lungs could influence lung cancer progression and prognosis

Bottom Line: Enrichment of the lungs with oral commensal microbes was associated with advanced stage disease, worse prognosis, and tumor progression in patients with lung cancer.

11 Nov 2020

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

High doses of vitamin C under study for treating COVID-19 may benefit some populations, but investigators exploring its potential in aging say key factors in effectiveness include levels of the natural transporter needed to get the vitamin inside cells.

11 Nov 2020

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

The action of metformin, the classic drug used to treat diabetes by stabilizing blood sugar, can be blocked by a molecule from the bacteria in our intestines, a University of Gothenburg study shows.

11 Nov 2020

Gene signature may help develop new therapies against advanced prostate cancer

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Microglia -- the brain's immune cells -- play a primary role in removing cellular debris from the brain. According to a recent study by a Nagoya University-led research team in Japan, another kind of brain cell, called astrocyte, is also involved in removing debris as a backup to microglia.

11 Nov 2020

T Cell News and Research

Latest T Cell News and Research

Research shows a unique T cell receptor repertoire in MIS-C patients

Men and women may require different brain tumor therapy, study finds

Biologists investigate how molecular chaperones dissolve protein aggregates linked to Parkinson's

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Discovery of novel hidden gene in SARS-CoV-2

Researchers uncover potential genetic target for treating endometriosis

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Rheumatoid arthritis may increase risk of dying from COVID-19

Team sport improves blood pressure, vascular function in postmenopausal women

Researchers identify new prognostic markers for colon cancer

Microbes in the lungs could influence lung cancer progression and prognosis

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

Gene signature may help develop new therapies against advanced prostate cancer

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Study: SphK2 enzyme regulates immune cell responses during viral infection

Underrepresented minorities are at increased risk for AL amyloidosis

Optical technique could transform accuracy and detection of biomechanical alterations of cells

Preliminary analysis of xenograft versus organoids

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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