T Cell News and Research

Latest T Cell News and Research

Simple blood test can detect a wide range of diseases

In diagnostic medicine, biopsies, where a sample of tissue is extracted for analysis, is a common tool for the detection of many conditions. But this approach has several drawbacks - it can be painful, doesn't always extract the diseased tissue, and can only be used in a sufficiently advanced disease stage, making it, in some cases, too late for intervention.

9 Feb 2021

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of free fatty acids (FFAs). These β cell-derived miR-29s are delivered to the liver, promoting insulin resistance and enhancing hepatic glucose output.

9 Feb 2021

New machine-learning algorithm estimates number of COVID-19 cases in the U.S.

World health experts have long suspected that the incidence of COVID-19 has been higher than reported. Now, a machine-learning algorithm developed at UT Southwestern estimates that the number of COVID-19 cases in the U.S. since the pandemic began is nearly three times that of confirmed cases.

8 Feb 2021

Differences in gene readouts may shed light on mental disorders

A new study suggests that differences in the expression of gene transcripts - readouts copied from DNA that help maintain and build our cells - may hold the key to understanding how mental disorders with shared genetic risk factors result in different patterns of onset, symptoms, course of illness, and treatment responses

8 Feb 2021

New study describes the evolutionary tale of poisonous butterflies

The Atala butterfly (Eumaeus atala) and its five closest relatives in the genus Eumaeus like to display their toxicity.

8 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers.

8 Feb 2021

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

In a recent medRxiv preprint publication, the team led by Professor Ravindra K. Gupta has assessed the real-world immune responses following the vaccination against the SARS-CoV-2. The team measured 1) IFN-gamma (interferon-gamma) T cell responses, 2) both total IgG Spike/ IgG Spike RBD (receptor binding domain) and 3) neutralizing antibody responses to Spike in sera.

8 Feb 2021

Researchers find new clues to how SARS-CoV-2 infects cells

The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors that could be important players in the process.

8 Feb 2021

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

A new nanoparticle-based drug can boost the body's innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown.

8 Feb 2021

Brain protein responsible for causing Alzheimer's disease also plays a protective role

Findings from a new study on Alzheimer's disease (AD), led by researchers at the University of Saskatchewan, could eventually help clinicians identify people at highest risk for developing the irreversible, progressive brain disorder and pave the way for treatments that slow or prevent its onset.

8 Feb 2021

Researchers identify a new drug target for Ebola, Marburg viruses

Ebola and Marburg are among the most deadly viruses, with mortality rates from these infections ranging from 25% to 90%.

8 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Researchers gain insight into the biological processes of chytrid fungus

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

8 Feb 2021

Moderna's COVID-19 vaccine effective against emerging variants

Researchers have conducted a study showing that the Moderna mRNA-1273 vaccine effectively protects against recently emerged variants of SARS-CoV-2 – the agent that causes COVID-19.

8 Feb 2021

Stopping cell recycling could help treat HER2-positive breast cancer

Recycling cans and bottles is a good practice. It helps keep the planet clean. The same is true for recycling within cells in the body. Each cell has a way of cleaning out waste in order to regenerate newer, healthier cells. This "cell recycling" is called autophagy.

8 Feb 2021

Bernese researchers develop a second generation lung-on-chip

The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs.

8 Feb 2021

Is a ten day isolation period for COVID-19 patients long enough?

In a new study researchers at the Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, Brazil, reported that mild COVID-19 patients can still be infectious at day 10 from the illness onset, even in the absence of symptoms.

8 Feb 2021

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

A team of researchers recently examined the SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epithelia.

8 Feb 2021

Bioengineered ankyrin compounds show high in vitro activity against SARS-CoV-2 mutants

A new study describes the use of DARPin (designed ankyrin repeat proteins) therapeutic agents, each of which contains three different DARPin domains within the same molecule.

8 Feb 2021

T Cell News and Research

Latest T Cell News and Research

Simple blood test can detect a wide range of diseases

Pancreatic β cells secrete miR-29 in response to high levels of free fatty acids

New machine-learning algorithm estimates number of COVID-19 cases in the U.S.

Differences in gene readouts may shed light on mental disorders

New study describes the evolutionary tale of poisonous butterflies

HIV: New therapeutic approach to restore the effectiveness of immune cells

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

Researchers find new clues to how SARS-CoV-2 infects cells

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

Brain protein responsible for causing Alzheimer's disease also plays a protective role

Researchers identify a new drug target for Ebola, Marburg viruses

Study implicates disruption in prenatal neurogenesis in the development of ASDs

Researchers gain insight into the biological processes of chytrid fungus

Moderna's COVID-19 vaccine effective against emerging variants

Stopping cell recycling could help treat HER2-positive breast cancer

Bernese researchers develop a second generation lung-on-chip

Is a ten day isolation period for COVID-19 patients long enough?

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

Bioengineered ankyrin compounds show high in vitro activity against SARS-CoV-2 mutants

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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