Gene News and Research

Latest Gene News and Research

How chromatin compartmentalization affects DNA damage response

Researchers uncover novel insights into how chromatin compartmentalization influences the DNA damage response (DDR) after double-stranded breaks (DSBs), shedding light on the mechanisms behind genomic integrity maintenance and the risk of translocations. Their findings reveal the importance of chromosomal design in DNA repair and the potential implications for genome stability and cancer translocations.

22 Oct 2023

Global surge of highly pathogenic avian influenza H5N1

A recent study published in Nature sheds light on the complex dynamics of highly pathogenic avian influenza (HPAI) H5N1 since 2021, uncovering critical shifts in the virus's behavior and providing insights for more effective mitigation strategies. The research emphasizes the importance of understanding the ecological and virological factors driving the intensified global activity of HPAI H5N1 to better prepare for and manage future outbreaks.

22 Oct 2023

Decoding schizophrenia: insights and impacts from genetic discoveries

A recent study in Molecular Psychiatry delves into the genetic architecture of schizophrenia, uncovering insights into common and rare genetic variants, treatment resistance, and the evolutionary paradox of the disorder. This research highlights the complex nature of schizophrenia and the need for a transdiagnostic approach to psychiatric research.

22 Oct 2023

Scientists develop gene therapy approach for rare paralyzing disease

The 50 families stretch from the Netherlands and the United Kingdom to the United States and China. Each family has a child who is paralyzed from a mutation in a single gene named Contactin-Associated Protein 1 (Cntnap1).

20 Oct 2023

New rice discovery could be good news diabetics and rice lovers

Good news for those who can't get enough of rice but are worried about their sugar and carb intakes.

20 Oct 2023

New funding from Breast Cancer Now supports research on treatment-resistant ER-positive breast cancer

Researchers are investigating how the most common type of breast cancer resists hormone therapy, thanks to new funding from Breast Cancer Now.

20 Oct 2023

Low serotonin levels observed in long COVID and other viral infections

Researchers identify a pathophysiological mechanism linking serotonin reduction to the multifaceted etiology of post-acute sequelae of COVID-19.

20 Oct 2023

Ferroptosis regulation of GLS2 as a potential therapeutic strategy against liver diseases

A new editorial paper was published in Oncotarget's Volume 14 on October 19, 2023, entitled, "GLS2 shapes ferroptosis in hepatocellular carcinoma."

19 Oct 2023

Plant geneticists explore predictability of natural and CRISPR mutations

For tens of thousands of years, evolution shaped tomatoes through natural mutations. Then, humans came along. For centuries, we've bred and cherry-picked tomatoes with our preferred traits.

19 Oct 2023

Brain natriuretic peptide plays a role in activating atopic dermatitis

Researchers from North Carolina State University have pinpointed a particular peptide's role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition.

19 Oct 2023

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Patients with multiple myeloma treated with idecabtagene vicleucel, known as "ide-cel," a chimeric antigen receptor (CAR) T-cell therapy, had no difference in overall survival outcomes regardless of race and ethnicity, according to a study published in Blood Advances.

19 Oct 2023

Common challenges when seeking market access for rare disease therapies

In this interview, News Medical speaks to Donovan Quill, Executive Vice President of Growth & Strategy at AscellaHealth about the recurring challenges met when seeking market access for rare disease therapies.

From AscellaHealth, LLC. 19 Oct 2023

Research reveals new way viruses suppress the CRISPR-Cas immune systems of bacteria

A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.

18 Oct 2023

Study sheds light on why women are more prone to ACL injuries

Injuries of the anterior cruciate ligament (ACL), located in the knee, are typically thought to be caused by acute traumatic events, such as sudden twists.

18 Oct 2023

Deep learning algorithm identifies antimalarial drug as promising treatment for osteoporosis

Artificial intelligence has exploded in popularity and is being harnessed by some scientists to predict which molecules could treat illnesses, or to quickly screen existing medicines for new applications.

18 Oct 2023

Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.

17 Oct 2023

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

The Foundation for Angelman Syndrome Therapeutics (FAST) announced today that the non-profit organization has entered into an exclusive global collaborative research and development agreement with the University of Pennsylvania to develop an investigational adeno-associated virus (AAV) gene therapy for Angelman syndrome (AS).

17 Oct 2023

Strengthening the immune system to fight cytomegalovirus on its own

Some viruses can be dormant throughout a person's life and cause no harm but become dangerous when the immune system is weakened.

17 Oct 2023

Mitochondrial protein CHCHD2 plays important role in glioblastoma progression

Glioblastoma is the most common type of brain tumor that affects adults and, unfortunately, still remains incurable. In a new study, researchers have demonstrated that a specific mitochondrial protein plays an important role in glioblastoma, and can therefore be used as a potential target to reduce tumors.

17 Oct 2023

Texas A&M researchers win NIH grant to study metabolism in people with Down syndrome

A team of researchers at the Texas A&M University School of Veterinary Medicine & Biomedical Sciences (VMBS) has received a grant from the National Institutes of Health (NIH) to research metabolism in people with Down syndrome.

17 Oct 2023

Gene News and Research

Latest Gene News and Research

How chromatin compartmentalization affects DNA damage response

Global surge of highly pathogenic avian influenza H5N1

Decoding schizophrenia: insights and impacts from genetic discoveries

Scientists develop gene therapy approach for rare paralyzing disease

New rice discovery could be good news diabetics and rice lovers

New funding from Breast Cancer Now supports research on treatment-resistant ER-positive breast cancer

Low serotonin levels observed in long COVID and other viral infections

Ferroptosis regulation of GLS2 as a potential therapeutic strategy against liver diseases

Plant geneticists explore predictability of natural and CRISPR mutations

Brain natriuretic peptide plays a role in activating atopic dermatitis

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Common challenges when seeking market access for rare disease therapies

Research reveals new way viruses suppress the CRISPR-Cas immune systems of bacteria

Study sheds light on why women are more prone to ACL injuries

Deep learning algorithm identifies antimalarial drug as promising treatment for osteoporosis

Lung chip model offers new insights into how radiation damages the lungs

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

Strengthening the immune system to fight cytomegalovirus on its own

Mitochondrial protein CHCHD2 plays important role in glioblastoma progression

Texas A&M researchers win NIH grant to study metabolism in people with Down syndrome

eBook: Using iPSCs models for human disease research and drug discovery eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production