Gene News and Research

Latest Gene News and Research

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

16 Nov 2023

Molecular trap offers hope for ALS treatment

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control.

16 Nov 2023

AI model predicts patient outcomes across multiple cancer types

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.

16 Nov 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

The frequency of viral rebound (VR) among acute coronavirus disease 2019 patients.

16 Nov 2023

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Pancreatic cancer is tricky to manage because it spreads easily and early, and the tumors have a unique biological makeup.

15 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model."

15 Nov 2023

New study investigates role of rare gene variants in IBD risk for African Americans

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

15 Nov 2023

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks.

15 Nov 2023

Study sheds light on specific variants responsible for rare and serious disorder

Many disorders are caused by genetic variants; to make matters worse, the genetic origin of most disorders remains unknown.

15 Nov 2023

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

RNA-based molecular subtypes modestly improved predictions for pathologic downstaging in muscle-invasive bladder cancer.

15 Nov 2023

Amelia Lavenski's seizure-free journey with the ketogenic diet

Amelia Lavenski is a 4-year-old girl from Anne Arundel County, Maryland, who has a bright personality and loves laughing and Mickey Mouse.

15 Nov 2023

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

5q-spinal muscular atrophy (5q-SMA) is one of the more common types of spinal muscular atrophy (SMA) affecting around one in ten thousand individuals worldwide.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

New approach to CAR T cell therapy may extend treatment effectiveness

CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize and attack cancer cells.

14 Nov 2023

Study reveals mechanisms underlying non-suppressible HIV viremia

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

14 Nov 2023

Gene therapy for rare diseases: A decade of progress and remaining challenges

A new review article in the peer-reviewed journal Human Gene Therapy summarizes the significant milestones in the development of gene therapy medicinal products that have facilitated the treatment of a significant number of rare diseases.

14 Nov 2023

Gene News and Research

Latest Gene News and Research

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Molecular trap offers hope for ALS treatment

AI model predicts patient outcomes across multiple cancer types

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study sheds new light on key cellular processes involved in Parkinson's disease progression

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

New study investigates role of rare gene variants in IBD risk for African Americans

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Study sheds light on specific variants responsible for rare and serious disorder

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

Amelia Lavenski's seizure-free journey with the ketogenic diet

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

New research explores the unique effects of ADHD medications on Drosophila brain cells

New approach to CAR T cell therapy may extend treatment effectiveness

Study reveals mechanisms underlying non-suppressible HIV viremia

Gene therapy for rare diseases: A decade of progress and remaining challenges

Genomics - Industry Focus eBook (2nd edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production