Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Elan second quarter total revenue increases 6% to $288.0 million

Elan Corporation, plc today reported its second quarter and first half 2012 financial results.

25 Jul 2012

Moderate-to-severe TBI can disrupt proteins that regulate enzyme associated with Alzheimer's

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer's disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer's.

25 Jul 2012

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Take a millionth of a human brain and squeeze it into a special chamber the size of a mustard seed. Link it to a second chamber filled with cerebral spinal fluid and thread both of them with artificial blood vessels in order to create a microenvironment that makes the neurons and other brain cells behave as if they were in a living brain. Then surround the chambers with a battery of sensors that monitor how the cells respond when exposed to minute quantities of dietary toxins, disease organisms or new drugs under development.

25 Jul 2012

Watching YouTube videos may help treat benign paroxysmal positional vertigo

Watching videos on YouTube may be a new way to show the treatment for a common cause of vertigo, which often goes untreated by physicians, according to a study published in the July 24, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2012

Topline results from first of four Phase 3 studies of Pfizer's bapineuzumab for Alzheimer's

Pfizer Inc. announced today that the co-primary clinical endpoints, change in cognitive and functional performance compared to placebo, were not met in the Janssen Alzheimer Immunotherapy R&D LLC (Janssen AI)-led Phase 3 trial of intravenous (IV) bapineuzumab in patients with mild-to-moderate Alzheimer's disease who carry the ApoE4 (apolipoprotein E epsilon 4) genotype.

24 Jul 2012

Researchers identify new class of compounds that inhibit spread of prions

A team of University of Alberta researchers has identified a new class of compounds that inhibit the spread of prions, misfolded proteins in the brain that trigger lethal neurodegenerative diseases in humans and animals.

24 Jul 2012

Top-line result from Pfizer Bapineuzumab Phase 3 studies on Alzheimer's

Elan Corporation, plc announced today that Pfizer has issued a top-line result in the first of four Bapineuzumab Phase 3 studies carried out by Pfizer and Janssen AI.

24 Jul 2012

Protein associated with Huntington’s and other neurodegenerative diseases has several brain-specific forms

A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research project funded by the Austrian Science Fund FWF, the findings of which have now been published in the journal Human Molecular Genetics.

23 Jul 2012

FDA grants accelerated approval for Kyprolis to treat multiple myeloma

Ligand Pharmaceuticals Incorporated today announced that its licensee, Onyx Pharmaceuticals, received accelerated approval from the U.S. Food and Drug Administration (FDA) for Kyprolis (carfilzomib) for Injection, a proteasome inhibitor indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

Research roundup: Gastric bypass costs, paying for psychotherapy

Health Expenditures Among High-Risk Patients After Gastric Bypass and Matched Controls -- A few studies have shown that bariatric surgery can help reduce health care spending by obese patients, particularly those with conditions such as diabetes. This latest study looked at 847 patients who received bariatric surgery through the Veterans Affairs medical system. Inpatient and outpatient spending both before and after surgery were compared to 847 obese patients who did not have the operation.

21 Jul 2012

Janssen-Cilag receives positive opinion from EMA CHMP for DACOGEN

Janssen-Cilag International NV announced today that the Committee for Medical Products for Human Use (CHMP) of the European Medicines Agency (EMA) has granted a positive opinion recommending approval of DACOGEN (decitabine) for Injection.

21 Jul 2012

Scientists uncover how internal mechanisms in nerve cells wire the brain

Scientists at the University of Manchester have uncovered how the internal mechanisms in nerve cells wire the brain. The findings open up new avenues in the investigation of neurodegenerative diseases by analysing the cellular processes underlying these conditions.

21 Jul 2012

Study demonstrates how nerve stimulation paired with specific experiences can reorganize the brain

UT Dallas researchers recently demonstrated how nerve stimulation paired with specific experiences, such as movements or sounds, can reorganize the brain. This technology could lead to new treatments for stroke, tinnitus, autism and other disorders.

20 Jul 2012

Epithilone D effective in preventing Alzheimer's in animal models

While clinical trial results are being released regarding drugs intended to decrease amyloid production - thought to contribute to decline in Alzheimer's disease - clinical trials of drugs targeting other disease proteins, such as tau, are in their initial phases.

20 Jul 2012

Impaired frontostriatal circuitry linked to cognitive defects in PD

Reduced activation of the frontostriatal circuits may underlie the mild cognitive impairment often seen in patients with early Parkinson’s disease, say researchers.

19 Jul 2012

New AAN guideline recommends several treatments for people with Huntington's chorea

A new guideline released by the American Academy of Neurology recommends several treatments for people with Huntington's disease who experience chorea—jerky, random, uncontrollable movements that can make everyday activities challenging.

19 Jul 2012

Bryologs more potent than prostratin in treating HIV

Thanks to antiretrovirals, an AIDS diagnosis hasn't been a death sentence for nearly two decades. But highly active antiretroviral therapy, or HAART, is also not a cure.

19 Jul 2012

Statistical method uses evolutionary information to enhance identification of disease-associated alleles

A book containing misprints may cause annoyance for the reader, but typos in an individual's genetic blueprint (DNA) can mean serious disease or even death. The search for genetic correlates for the wide range of diseases plaguing humankind has inspired a wealth of research falling under the heading of genome-wide association studies (GWAS).

19 Jul 2012

New research sheds light on pluripotency

New research at the Hebrew University of Jerusalem sheds light on pluripotency-the ability of embryonic stem cells to renew themselves indefinitely and to differentiate into all types of mature cells.

19 Jul 2012

Dementia patients allowed to live at home thanks to new research program

A Johns Hopkins research program that brought resources and counselors to elderly Baltimore residents with memory disorders such as dementia significantly increased the chance they could continue to live successfully at home, a preference for most of them.

19 Jul 2012

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Elan second quarter total revenue increases 6% to $288.0 million

Moderate-to-severe TBI can disrupt proteins that regulate enzyme associated with Alzheimer's

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Watching YouTube videos may help treat benign paroxysmal positional vertigo

Topline results from first of four Phase 3 studies of Pfizer's bapineuzumab for Alzheimer's

Researchers identify new class of compounds that inhibit spread of prions

Top-line result from Pfizer Bapineuzumab Phase 3 studies on Alzheimer's

Protein associated with Huntington’s and other neurodegenerative diseases has several brain-specific forms

FDA grants accelerated approval for Kyprolis to treat multiple myeloma

Research roundup: Gastric bypass costs, paying for psychotherapy

Janssen-Cilag receives positive opinion from EMA CHMP for DACOGEN

Scientists uncover how internal mechanisms in nerve cells wire the brain

Study demonstrates how nerve stimulation paired with specific experiences can reorganize the brain

Epithilone D effective in preventing Alzheimer's in animal models

Impaired frontostriatal circuitry linked to cognitive defects in PD

New AAN guideline recommends several treatments for people with Huntington's chorea

Bryologs more potent than prostratin in treating HIV

Statistical method uses evolutionary information to enhance identification of disease-associated alleles

New research sheds light on pluripotency

Dementia patients allowed to live at home thanks to new research program

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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