Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

22 Jul 2025

Mount Sinai researcher uncovers how the brain and body interact in aging and depression

In a comprehensive Genomic Press interview published in Brain Medicine today, Dr. Hamilton Se-Hwee Oh reveals groundbreaking insights into the complex dialogue between our brains and bodies that fundamentally shapes aging, depression, and neurodegenerative disease.

22 Jul 2025

APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s

Researchers discovered that people carrying the APOE ε4 gene variant share a unique immune-related protein signature across their blood, brain, and cerebrospinal fluid—regardless of neurodegenerative disease diagnosis. This signature reveals a fundamental, disease-independent vulnerability linked to APOE ε4, reframing our understanding of genetic risk in conditions like Alzheimer's, Parkinson’s, ALS, and FTD.

21 Jul 2025

Combination of two cancer drugs could treat the most common form of dementia

A study comparing the gene expression signature of Alzheimer's disease with those elicited by 1,300 approved drugs found a combination of two cancer medications that could treat the most common form of dementia.

21 Jul 2025

Heart-healthy habits can improve overall physical and psychological well-being

A new study from Emory University reveals that maintaining optimal cardiovascular health can significantly improve overall physical and psychological well-being.

18 Jul 2025

New machine learning model revolutionizes protein simulations

An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin introduces a breakthrough in protein simulation.

18 Jul 2025

Understanding brain activity during sleep to detect early neurological changes

"Complex processes are going on in the brain when we sleep," says Dr Karolina Armonaitė, a neuroscientist from Kaunas University of Technology, Lithuania. According to her, a more precise understanding of what happens in different areas of the cerebral cortex during sleep can help diagnose sleep disorders and neurological diseases more accurately.

18 Jul 2025

Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

17 Jul 2025

AI-guided patient stratification boosts Alzheimer’s trial outcomes and efficiency

Scientists have used an AI model to reassess the results of a completed clinical trial for an Alzheimer's disease drug.

17 Jul 2025

Standardized brain cell atlas to accelerate Parkinson's and Alzheimer's research

Researchers now have a powerful new way to understand the types of brain cells that are affected in neurodegenerative diseases and to uncover connections between conditions such as Parkinson's, Alzheimer's, and other forms of dementia.

17 Jul 2025

Research suggests a new strategy to improve blood flow to the brain to battle Alzheimer's

New University of Virginia School of Medicine research suggests an unexpected way doctors may be able to improve blood flow to the brain to battle Alzheimer's and other neurodegenerative diseases.

16 Jul 2025

Music therapy approach can ease distress in dementia patients

A new treatment that uses music therapy on dementia wards could improve care and support for some of the NHS's most vulnerable patients.

16 Jul 2025

TTUHSC researcher focuses on how brain endothelial cells handle stressors of neuroinflammation

Each year in the U.S., approximately 2.5 million people suffer traumatic brain injuries (TBIs). About 50,000 of these injuries will result in death, and more than 80,000 will lead to permanent disability.

16 Jul 2025

Heart healthy habits boost overall body health and longevity

People who had more heart-healthy habits and factors, as assessed by the American Heart Association's Life's Simple 7 metrics for ideal cardiovascular health, had more positive benefits for whole body health, according to a review of research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

16 Jul 2025

Childhood heart health predicts lifelong well-being, study finds

Optimal heart health from birth through adolescence, as measured by a combination of metrics, leads to long-lasting cardiovascular and overall physical, cognitive and mental health, according to the systematic review published in the Journal of the American Heart Association.

16 Jul 2025

UK Biobank completes world's largest whole-body imaging project

In a remarkable achievement that is already impacting how we detect and diagnose disease, UK Biobank has completed the world's largest whole body imaging project, scanning the brains, hearts, abdomens, blood vessels, bones and joints of 100,000 volunteers.

16 Jul 2025

Loneliness amplifies cognitive decline in individuals with hearing loss

Isolation, communication difficulties, reduced alertness — hearing impairment or loss is a real challenge in daily life. Over time, it can also become a risk factor for cognitive decline. A team from the University of Geneva (UNIGE) analyzed data from 33,000 older adults across Europe to examine the combined impact of hearing loss and loneliness on memory.

16 Jul 2025

Brain's tiny region dictates how memories are formed and separated

Life may unfold as a continuous stream, but our memories tell a different story. We do not recall the past as one long, unbroken text. Instead, we remember it as a series of meaningful events, like how sentences are structured with grammar and punctuation.

16 Jul 2025

Yoga, Tai Chi, walking and jogging found to improve sleep and ease insomnia

Yoga, Tai Chi, walking and jogging may be the best forms of exercise to improve sleep quality and ease insomnia, suggest the findings of a comparative pooled data analysis published in the online journal BMJ Evidence Based Medicine.

15 Jul 2025

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

University of New Mexico researchers have received funding to launch an early-stage clinical trial of a vaccine engineered to clear pathological tau protein from the brains of patients suffering from Alzheimer's dementia.

15 Jul 2025

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes

Mount Sinai researcher uncovers how the brain and body interact in aging and depression

APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s

Combination of two cancer drugs could treat the most common form of dementia

Heart-healthy habits can improve overall physical and psychological well-being

New machine learning model revolutionizes protein simulations

Understanding brain activity during sleep to detect early neurological changes

Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

AI-guided patient stratification boosts Alzheimer’s trial outcomes and efficiency

Standardized brain cell atlas to accelerate Parkinson's and Alzheimer's research

Research suggests a new strategy to improve blood flow to the brain to battle Alzheimer's

Music therapy approach can ease distress in dementia patients

TTUHSC researcher focuses on how brain endothelial cells handle stressors of neuroinflammation

Heart healthy habits boost overall body health and longevity

Childhood heart health predicts lifelong well-being, study finds

UK Biobank completes world's largest whole-body imaging project

Loneliness amplifies cognitive decline in individuals with hearing loss

Brain's tiny region dictates how memories are formed and separated

Yoga, Tai Chi, walking and jogging found to improve sleep and ease insomnia

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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