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Scientists use transcription factors to increase insulin production in diabetic mice

A group of Japanese scientists has used gene therapy to deliver three insulin transcription factors, MafA, PDX-1, and NeuroD, to the livers of diabetic mice. As a result, the mice experienced an increase in insulin gene expression and insulin production, raising the possibility that this could eventually be used to treat diabetes.

13 Apr 2005

New test for cancer, more sensitive than any existing techniques

Speaking at the Institute of Physics conference Physics 2005 in Warwick, scientists will reveal a new test for cancer, more sensitive than any existing technique and capable of predicting for the first time whether a tumour has spread.

12 Apr 2005

Swedish team find gene with link to major diseases

In an exciting new discovery, which could affect millions of people, scientists from the Karolinska Institute and the Centre for Molecular Medicine (CMM) in Stockholm, Sweden, have identified a gene which links autoimmune diseases with cardiovascular diseases.

12 Apr 2005

Largest "gene deserts" yet discovered in the human genome sequence

A detailed analysis of chromosomes 2 and 4 has detected the largest "gene deserts" known in the human genome and uncovered more evidence that human chromosome 2 arose from the fusion of two ancestral ape chromosomes, researchers supported by the National Human Genome Research Institute (NHGRI).

6 Apr 2005

An exceptionally effective lead-detection protein

Scientists from the U.S. Department of Energy’s Brookhaven National Laboratory and the University of Chicago have discovered that a member of a well-known protein family is better at detecting lead than any other known substance.

5 Apr 2005

Immune cells in the liver travel in the liver's blood vessels with surprising speed and agility

Scientists at New York University School of Medicine viewing the actual journey of immune cells in the liver have found that these cells travel in the liver's blood vessels with surprising speed and agility.

4 Apr 2005

Rabies, HIV, cancer and malaria could all be prevented with pills in the future

Rabies, HIV, cancer and malaria could all be prevented with pills in the future, if a new technique using specially modified viruses to deliver vaccines is adopted, according to scientists speaking today (Tuesday, 05 April 2005) at the Society for General Microbiology's 156th Meeting at Heriot-Watt University, Edinburgh.

4 Apr 2005

Scientists identify novel regulator of telomere homeostasis

Each of our 46 chromosomes is capped by a telomere – a long stretch of repeated DNA (TTAGG). Telomeres play a key protective function in our cells, and now Dr. In Kwon Chung and colleagues at Yonsei University (Seoul, Korea) and the University of Central Florida reveal a novel mechanism to modulate telomere length.

3 Apr 2005

Dozens of new genes identified in X chromosome

By intensely and systematically comparing the human X chromosome to genetic information from chimpanzees, rats and mice, a team of scientists from the United States and India has uncovered dozens of new genes, many of which are located in regions of the chromosome already tied to disease.

3 Apr 2005

Protein Mnd2 protects chromosome bonds

The protein Mnd2 inhibits premature separation of chromosomes during the formation of gametes. The now published discovery of this regulatory function may help to understand the origin of some common congenital chromosome defects.

30 Mar 2005

New color-coded test for protein folding

Every protein--from albumin to testosterone--is folded into a unique, three-dimensional shape that allows it to function properly. Now Stanford University scientists have developed a simple test that instantly changes color when a protein molecule attached to a gold nanoparticle folds or unfolds.

28 Mar 2005

Antibodies from tobacco plants protect against anthrax

Scientists have produced, in tobacco plants, human antibodies that could be used to treat anthrax exposure. They reported their findings at the 2005 American Society for Microbiology Biodefense Research Meeting.

23 Mar 2005

Discovery that sheds new light upon the growth and development of human natural killer (NK) cells

Scientists here have made a major discovery that sheds new light upon the growth and development of human natural killer (NK) cells, powerful but somewhat mysterious components of the body’s immune system that are the first line of defense against cancer and infectious diseases.

23 Mar 2005

Tiny scaffolding allows stem cells to become working fat cells

Researchers here have used a new microscopic, three-dimensional scaffolding to coax mouse stem cells to transform themselves into fat cells, and then to function identical to how fat cells naturally do in the body.

22 Mar 2005

Green alga closes wounds by means of enzymatic activation of a cross-linking protein

A small wound is painful, but is normally not a problem. Like all multicellular organisms, our bodies form new tissue around the damaged cells. Single-celled organisms cannot do this. In order to survive an injury, they have to quickly repair the cell itself. Large single-celled organisms, such as the green alga Caulerpa taxifolia, which can be several meters long, are especially at risk for injuries.

22 Mar 2005

Structure of key protein in innate immune response

In a report published in the Journal of Biological Chemistry, scientists in Korea announced their elucidation of three-dimensional structure of CD14 and showed how it is perfectly suited to bind to certain bacterial products.

21 Mar 2005

Genetically modified plants are to be used to fight against HIV, tuberculosis, diabetes and rabies

Genetically modified (GM) plants are to be used to grow vaccines for use in the worldwide fight against HIV, tuberculosis, diabetes and rabies thanks to a grant of 12 million euros from the EU’s Sixth Framework Programme (FP6).

21 Mar 2005

Discovery of a single mutation responsible for a number of blood disorders

Myeloproliferative disorders form a range of haematological malignant diseases, with three main members: polycythaemia vera, essential thrombocythaemia, and idiopathic myelofi- brosis. The disorders are characterised by overactive production of blood cells and can lead to thrombosis, haemorrhage or acute myeloid leukaemia.

21 Mar 2005

X-Chromosome has the big story!!

The human genome is said by some to be the "book of life," and the X-chromosome a large part of the the plot. A team of genome researchers have described the nature of this mysterious "chapter" in the DNA story.

17 Mar 2005

UK grows stem cells free of animal products

Dr Paul de Souza and scientists at the Roslin Institute have successfully created human cells without using animal products.

17 Mar 2005

Medical Science News

Scientists use transcription factors to increase insulin production in diabetic mice

New test for cancer, more sensitive than any existing techniques

Swedish team find gene with link to major diseases

Largest "gene deserts" yet discovered in the human genome sequence

An exceptionally effective lead-detection protein

Immune cells in the liver travel in the liver's blood vessels with surprising speed and agility

Rabies, HIV, cancer and malaria could all be prevented with pills in the future

Scientists identify novel regulator of telomere homeostasis

Dozens of new genes identified in X chromosome

Protein Mnd2 protects chromosome bonds

New color-coded test for protein folding

Antibodies from tobacco plants protect against anthrax

Discovery that sheds new light upon the growth and development of human natural killer (NK) cells

Tiny scaffolding allows stem cells to become working fat cells

Green alga closes wounds by means of enzymatic activation of a cross-linking protein

Structure of key protein in innate immune response

Genetically modified plants are to be used to fight against HIV, tuberculosis, diabetes and rabies

Discovery of a single mutation responsible for a number of blood disorders

X-Chromosome has the big story!!

UK grows stem cells free of animal products

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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