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Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small cell lung cancer.

31 Oct 2025

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.

31 Oct 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

Proimmune Ltd introduces Prove® SL Self-Loading MHC Class I Monomers to improve T cell research flexibility

ProImmune Ltd, a global leader in life science reagents and services, today announced the launch of its new ProVE® SL Self-Loading MHC Class I Monomers.

31 Oct 2025

Global study suggests potential for universal vaccine against Haemophilus influenzae

A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be possible, experts say.

31 Oct 2025

Massive cross-ancestry study explains why obesity risks differ around the world

A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.

31 Oct 2025

COVID-19 in pregnancy may raise autism and neurodevelopmental disorder risk

Children born to mothers who contracted COVID-19 during pregnancy face a 29% higher likelihood of developmental disorders by age three, including speech, motor, and autism-spectrum delays. The risk was greatest for male offspring and infections occurring in the third trimester.

30 Oct 2025

Common viruses sharply raise heart attack and stroke risk, major global review shows

In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.

30 Oct 2025

Bowhead whale’s secret to long life revealed: precision DNA repair may hold clues for human aging

Researchers discovered that bowhead whales achieve extraordinary longevity and cancer resistance through highly efficient and precise DNA repair mechanisms. A whale-specific protein, CIRBP, enhances genome stability even in human cells, revealing a potential pathway to strengthen DNA repair and slow aging.

30 Oct 2025

Study confirms PSA screening improves survival and safety

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

30 Oct 2025

Researchers uncover mechanism by which BRCA2-deficient tumors develop chemoresistance

One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited.

30 Oct 2025

Study uncovers neural mechanisms behind memory stabilization

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers.

30 Oct 2025

Study finds more commonalities between CTE and Alzheimer's disease at the genetic level

Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share similarities with Alzheimer's disease (AD), namely the buildup of a protein called tau in the brain.

30 Oct 2025

First-of-its-kind resource created to identify people with genetic risk for elevated 'bad' cholesterol

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated 'bad' cholesterol -- a major contributor to heart disease.

30 Oct 2025

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells.

30 Oct 2025

New method yields up to twice as many therapeutic myogenic cells as previous protocols

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

30 Oct 2025

Intraoperative radiation reduces the recurrence rate of pancreatic cancer

Using targeted radiation during surgery - referred to as intraoperative radiation - to eliminate pancreatic cancer cells that have spread to areas around the pancreas, investigators at Johns Hopkins have been able to reduce the recurrence rate around the pancreas to 5%.

30 Oct 2025

Minimal fibers enable communication between brain hemispheres

Just a few fibers are enough for the two hemispheres of the brain to communicate with each other. This was shown by a new international study led by Professor Dr Michael Miller (University of California, Santa Barbara) and Professor Dr Lukas J. Volz (Department of Neurology at University Hospital Cologne and the University of Cologne's Faculty of Medicine) in close collaboration with Professor Dr Christian Bien's team at the Bethel Epilepsy Centre (University Hospital OWL at Bielefeld University).

30 Oct 2025

Reducing ketone levels and increasing exercise capacity could help manage diabetic ketoacidosis

A researcher at the University of Houston finds management of diabetic ketoacidosis may center around reducing ketone levels in diabetic patients and increasing exercise capacity for better health outcomes.

30 Oct 2025

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Medical Research News

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

Proimmune Ltd introduces Prove® SL Self-Loading MHC Class I Monomers to improve T cell research flexibility

Global study suggests potential for universal vaccine against Haemophilus influenzae

Massive cross-ancestry study explains why obesity risks differ around the world

COVID-19 in pregnancy may raise autism and neurodevelopmental disorder risk

Common viruses sharply raise heart attack and stroke risk, major global review shows

Bowhead whale’s secret to long life revealed: precision DNA repair may hold clues for human aging

Study confirms PSA screening improves survival and safety

Researchers uncover mechanism by which BRCA2-deficient tumors develop chemoresistance

Study uncovers neural mechanisms behind memory stabilization

Study finds more commonalities between CTE and Alzheimer's disease at the genetic level

First-of-its-kind resource created to identify people with genetic risk for elevated 'bad' cholesterol

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

New method yields up to twice as many therapeutic myogenic cells as previous protocols

Intraoperative radiation reduces the recurrence rate of pancreatic cancer

Minimal fibers enable communication between brain hemispheres

Reducing ketone levels and increasing exercise capacity could help manage diabetic ketoacidosis

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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