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Understanding the interconnected roles of microbial, metabolic, and immune biomarkers in IBD

Inflammatory Bowel Disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory condition of the gastrointestinal tract with a rising global burden.

19 Jun 2025

New gene therapy strategy reactivates dormant genes to treat blood disorders

Researchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers.

19 Jun 2025

New meta-analysis highlights effective non-drug therapies for knee osteoarthritis

Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee osteoarthritis, according to a new meta-analysis publishing June 18, 2025 in the open-access journal PLOS One by Yuan Luo of the First People's Hospital of Neijiang, China.

19 Jun 2025

T cells play key role in early stages of Parkinson’s disease

Your T cells work hard to fight disease. Unfortunately, "friendly fire" from T cells can sometimes harm the body's healthy tissues.

19 Jun 2025

C-Path’s TRxA awards $250,000 grant to develop novel treatment for type 1 diabetes

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) proudly announced today a $250,000 grant award aimed at developing a novel treatment for type 1 diabetes (T1D).

19 Jun 2025

Intermittent fasting shows similar weight loss benefits to traditional diets

Intermittent fasting diets appear to have similar benefits to traditional calorie-restricted diets for weight loss, suggests an analysis of trial evidence published by The BMJ today.

19 Jun 2025

How early-life factors raise lifelong diabetes risks in youth

The surge in diabetes among young people highlights critical gaps in care and the urgent need for comprehensive preventative actions to address this crisis.

19 Jun 2025

Cognitive decline tied to gut microbes and nutritional access

A new study led in part by Mount Sinai researchers has found a compelling link between the composition of the gut microbiome and the risk of cognitive impairment (RCI) in adults, underscoring the complex role that both biology and social determinants-such as food insecurity-play in brain health.

18 Jun 2025

New screening method for Parkinson's analyzes odors in ear wax

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis.

18 Jun 2025

Researchers explore new approach to target rare epileptic disorders

Humans have tens of thousands of genes, many of which produce proteins essential to basic bodily functions.

18 Jun 2025

Can salt substitutes lower blood pressure in diabetes? A new Cochrane review aims to find out

Researchers will systematically review whether replacing regular sodium salt with alternatives like potassium or magnesium salts helps lower blood pressure in adults with diabetes. The protocol outlines a rigorous plan to evaluate blood pressure effects, safety, and adherence using data from RCTs and quasi-RCTs.

18 Jun 2025

Uppsala researchers create 3D-printed human nerve tissue model

With the aid of a 3D printer, researchers at Uppsala University have succeeded in creating a model that resembles human nerve tissue.

18 Jun 2025

Can a Japanese diet help with depression? Large study says yes

A large cross-sectional study of 12,499 Japanese workers found that higher adherence to traditional or modified Japanese diets was associated with a lower prevalence of depressive symptoms. The findings suggest that culturally rooted dietary patterns may support mental well-being, especially among educated adults.

18 Jun 2025

Equal access, unequal impact: Parkinson’s hits minorities harder in the UK

Researchers in East London found that South Asian and Black Parkinson’s disease patients experience more severe motor and cognitive symptoms than White patients. Despite similar access to diagnosis, disparities persist, highlighting the need for more inclusive and culturally sensitive care.

18 Jun 2025

Inhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancers

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

18 Jun 2025

Immune cell signatures explain variations in systemic sclerosis severity

Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients with the same disease exhibit different symptoms.

18 Jun 2025

Living near microplastic polluted waters linked to higher risk of heart and metabolic diseases

Living in a U.S. coastal county bordered by ocean waters with very high concentrations of microplastics may increase the risk of heart and metabolic diseases, such as Type 2 diabetes, coronary artery disease and stroke.

18 Jun 2025

New switchable CAR-T therapy enters phase 1 trial for advanced breast cancer

The Calibr-Skaggs Institute for Innovative Medicines, the drug development division of Scripps Research, today announced a milestone in cancer treatment with the dosing of the first patient in a phase 1 trial (NCT06878248) evaluating CLBR001 + ABBV-461, a modular, switchable chimeric antigen receptor T cell (sCAR-T) therapy in patients with advanced or metastatic breast cancer who have no suitable treatment options.

18 Jun 2025

CAR T-cell therapy successfully treats rare autoimmune disease of the peripheral nervous system

Physicians from Bochum have used a cancer treatment method to treat severe autoimmune diseases.

18 Jun 2025

Interferon pathway genes linked to treatment success in juvenile arthritis

A set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis (JIA) have been identified by researchers at UCL and Great Ormond Street Hospital for Children (GOSH), who are part of the CLUSTER Consortium.

18 Jun 2025

Medical Condition News

Understanding the interconnected roles of microbial, metabolic, and immune biomarkers in IBD

New gene therapy strategy reactivates dormant genes to treat blood disorders

New meta-analysis highlights effective non-drug therapies for knee osteoarthritis

T cells play key role in early stages of Parkinson’s disease

C-Path’s TRxA awards $250,000 grant to develop novel treatment for type 1 diabetes

Intermittent fasting shows similar weight loss benefits to traditional diets

How early-life factors raise lifelong diabetes risks in youth

Cognitive decline tied to gut microbes and nutritional access

New screening method for Parkinson's analyzes odors in ear wax

Researchers explore new approach to target rare epileptic disorders

Can salt substitutes lower blood pressure in diabetes? A new Cochrane review aims to find out

Uppsala researchers create 3D-printed human nerve tissue model

Can a Japanese diet help with depression? Large study says yes

Equal access, unequal impact: Parkinson’s hits minorities harder in the UK

Inhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancers

Immune cell signatures explain variations in systemic sclerosis severity

Living near microplastic polluted waters linked to higher risk of heart and metabolic diseases

New switchable CAR-T therapy enters phase 1 trial for advanced breast cancer

CAR T-cell therapy successfully treats rare autoimmune disease of the peripheral nervous system

Interferon pathway genes linked to treatment success in juvenile arthritis

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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